{"title":"Peptides for Cellular Energy \u0026 Mitochondrial Research","description":"\u003cp\u003eResearch compounds studied for cellular energy production, mitochondrial function and metabolic capacity. Every batch independently assayed by HPLC. Research use only.\u003c\/p\u003e","products":[{"product_id":"mots-c","title":"MOTS-C 30mg","description":"\u003cp\u003eMOTS-C is a mitochondrial-encoded peptide that originates from mitochondrial DNA rather than nuclear DNA. It is an essential compound in research related to cellular energy regulation and metabolic signaling.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eKey Features:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli data-path-to-node=\"8,0,0\"\u003e\n\u003cb data-path-to-node=\"8,0,0\" data-index-in-node=\"0\"\u003ePhysiological Stress\u003c\/b\u003e: Studies investigate how MOTS-C helps cells adapt to various forms of physiological stress.\u003c\/li\u003e\n\u003cli data-path-to-node=\"8,1,0\"\u003e\n\u003cb data-path-to-node=\"8,1,0\" data-index-in-node=\"0\"\u003eResponse Mechanisms\u003c\/b\u003e: It is used to explore the mechanisms of cellular adaptation, helping researchers understand how cells maintain homeostasis under pressure.\u003c\/li\u003e\n\u003cli data-path-to-node=\"8,2,0\"\u003e\n\u003cb data-path-to-node=\"8,2,0\" data-index-in-node=\"0\"\u003eAdaptation Pathways\u003c\/b\u003e: The peptide serves as a key subject in research involving the pathways through which mitochondria signal for cellular protection and adaptation.\u003c\/li\u003e\n\u003cli data-path-to-node=\"8,2,0\"\u003e\n\u003cb data-path-to-node=\"4,1,1,0,0\" data-index-in-node=\"0\"\u003ePurity\u003c\/b\u003e: Verified at 99% purity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb data-path-to-node=\"12,2,1,6,0\" data-index-in-node=\"0\"\u003eRegulatory Note:\u003c\/b\u003e Research Use Only.\u003c\/p\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":49172141736159,"sku":null,"price":79.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/8787\/3759\/files\/ChatGPT_Image_May_20_2026_11_51_43_PM.png?v=1779301325"},{"product_id":"nad","title":"NAD+","description":"\u003cstyle\u003e.pp-pdp{--nv:#0d2233;--tl:#3a9ab5;--ink:#1f2937;--mut:#5b6b7a;--ln:#e3e8ee;--sf:#f5f8fa;--gr:#1E9E5A;font-family:Montserrat,-apple-system,sans-serif;color:var(--ink);line-height:1.6;margin:34px 0 0;width:100%;max-width:100%;overflow-x:hidden;background:#fff;text-align:left}.pp-pdp *{box-sizing:border-box}.pp-pdp h2,.pp-pdp h3{color:var(--nv);font-weight:800;line-height:1.15;margin:0 0 14px}.pp-pdp p{color:var(--ink);margin:0 0 14px}.pp-pdp p:last-child{margin-bottom:0}.pp-pdp a{color:#0d6c8a}.pp-pdp .pp-in{max-width:1180px;margin:0 auto;padding:0 24px}.pp-pdp .pp-kick{color:var(--tl);font-size:12px;letter-spacing:2.16px;text-transform:uppercase;font-weight:600;margin:0 0 12px}.pp-pdp .pp-sec{padding:56px 0}.pp-pdp .pp-alt{background:var(--sf)}.pp-pdp .pp-sec h2{font-size:30px}.pp-pdp .pp-prose p{font-size:15.5px;color:var(--mut)}.pp-pdp .pp-prose p strong{color:var(--nv)}.pp-pdp .pp-wide{max-width:900px}.pp-pdp .pp-g2{display:grid;grid-template-columns:1.05fr .95fr;gap:48px;align-items:start}.pp-pdp .pp-media{position:sticky;top:24px}.pp-pdp .pp-img{width:100%;height:auto;display:block;border-radius:14px;border:1px solid var(--ln);background:#fff}.pp-pdp .pp-fig{margin:30px 0 0;max-width:900px}.pp-pdp .pp-facts{background:var(--nv);border-top:4px solid var(--tl);padding:28px 0}.pp-pdp .pp-facts .pp-in{display:grid;grid-template-columns:repeat(auto-fit,minmax(180px,1fr));gap:22px}.pp-pdp .pp-fi{text-align:center;padding:4px 14px;border-left:1px solid rgba(255,255,255,.14)}.pp-pdp .pp-fi:first-child{border-left:0}.pp-pdp .pp-fi b{display:block;color:#fff;font-weight:800;line-height:1.2;margin-bottom:8px}.pp-pdp .pp-fi .pp-v1{font-size:27px}.pp-pdp .pp-fi .pp-v2{font-size:17px}.pp-pdp .pp-fi .pp-v3{font-size:13.5px;font-weight:700;line-height:1.45}.pp-pdp .pp-fi span{display:block;color:var(--tl);font-size:11.5px;letter-spacing:1.4px;text-transform:uppercase;font-weight:700}.pp-pdp .pp-cards{display:grid;grid-template-columns:repeat(auto-fit,minmax(230px,1fr));gap:20px}.pp-pdp .pp-card{background:#fff;border:1px solid var(--ln);border-radius:12px;padding:24px;box-shadow:0 2px 10px rgba(13,34,51,.05)}.pp-pdp .pp-card .pp-num{display:block;font-size:12px;letter-spacing:1.4px;font-weight:800;color:var(--tl);margin-bottom:10px}.pp-pdp .pp-card p{font-size:14.5px;color:var(--mut);margin:0}.pp-pdp .pp-faq{max-width:880px}.pp-pdp .pp-ac{background:#fff;border:1px solid var(--ln);border-radius:10px;margin-bottom:12px;overflow:hidden}.pp-pdp .pp-ac summary{list-style:none;cursor:pointer;padding:18px 54px 18px 22px;position:relative;font-weight:700;font-size:16.5px;color:var(--nv)}.pp-pdp .pp-ac summary::-webkit-details-marker{display:none}.pp-pdp .pp-ac summary:after{content:\"\";position:absolute;right:24px;top:50%;width:9px;height:9px;border-right:2px solid var(--tl);border-bottom:2px solid var(--tl);transform:translateY(-70%) rotate(45deg);transition:transform .18s}.pp-pdp .pp-ac[open] summary:after{transform:translateY(-20%) rotate(-135deg)}.pp-pdp .pp-ac summary:hover{background:var(--sf)}.pp-pdp .pp-ac .pp-ab{padding:0 22px 20px;color:var(--mut);font-size:15px}.pp-pdp .pp-ac .pp-ab p{color:var(--mut);font-size:15px}.pp-pdp .pp-links{background:#fff;border-top:1px solid var(--ln);padding:34px 0 44px}.pp-pdp .pp-chips{display:flex;flex-wrap:wrap;gap:10px}.pp-pdp .pp-chip{display:inline-block;padding:10px 16px;border:1px solid var(--ln);border-radius:6px;background:#fff;color:var(--nv)!important;font-size:13.5px;font-weight:600;text-decoration:none;line-height:1.3}.pp-pdp .pp-chip:hover{border-color:var(--tl)}.pp-pdp .pp-chip-lead{background:var(--nv);color:#fff!important;border-color:var(--nv)}.pp-pdp .pp-chip-alt{background:var(--sf)} @media(max-width:900px){.pp-pdp .pp-g2{grid-template-columns:1fr;gap:28px}.pp-pdp .pp-media{position:static}.pp-pdp .pp-sec{padding:40px 0}.pp-pdp .pp-sec h2{font-size:24px}.pp-pdp .pp-in{padding:0 18px}.pp-pdp .pp-facts .pp-in{grid-template-columns:repeat(2,1fr);gap:18px}.pp-pdp .pp-fi{border-left:0;text-align:left;padding:0}.pp-pdp .pp-fi .pp-v1{font-size:22px}.pp-pdp .pp-cards{grid-template-columns:1fr} } @media(max-width:520px){.pp-pdp .pp-facts .pp-in{grid-template-columns:1fr}}.pp-pdp .pp-ov{border-left:4px solid var(--tl);background:var(--sf);border-radius:0 12px 12px 0;padding:26px 28px;max-width:900px}.pp-pdp .pp-ov p{font-size:16px;color:var(--ink)}.pp-pdp .pp-tldr{list-style:none;margin:18px 0 0;padding:16px 0 0;border-top:1px solid var(--ln)}.pp-pdp .pp-tldr li{display:flex;gap:14px;padding:6px 0;font-size:14.5px;color:var(--mut)}.pp-pdp .pp-tldr b{color:var(--nv);flex:0 0 148px}.pp-pdp .pp-card h3{font-size:15.5px;margin:0 0 8px;color:var(--nv);line-height:1.3}.pp-pdp .pp-more{margin-top:24px;max-width:900px}.pp-pdp .pp-more .pp-ab p{margin-bottom:12px}.pp-pdp .pp-dose{width:100%;border-collapse:collapse;margin:0 0 16px}.pp-pdp .pp-dose th,.pp-pdp .pp-dose td{text-align:left;padding:11px 14px;border-bottom:1px solid var(--ln);font-size:14.5px;color:var(--mut)}.pp-pdp .pp-dose th{background:var(--nv);color:#fff;font-size:11.5px;letter-spacing:1.2px;text-transform:uppercase;font-weight:700}.pp-pdp .pp-dose td:first-child{font-weight:700;color:var(--nv);white-space:nowrap}.pp-pdp .pp-step{counter-reset:s;list-style:none;padding:0;margin:0 0 18px}.pp-pdp .pp-step li{position:relative;padding:0 0 11px 34px;font-size:15px;color:var(--mut)}.pp-pdp .pp-step li:before{counter-increment:s;content:counter(s);position:absolute;left:0;top:1px;width:22px;height:22px;border-radius:50%;background:var(--tl);color:#fff;font-size:12px;font-weight:800;display:flex;align-items:center;justify-content:center}.pp-pdp .pp-warn{background:#fff6e5;border-left:4px solid #e0a33a;padding:13px 18px;border-radius:0 8px 8px 0;font-size:14.5px;color:var(--ink);margin:0 0 16px}.pp-pdp .pp-warn p{margin:0 0 6px;font-size:14.5px}.pp-pdp .pp-warn p:last-child{margin:0}.pp-pdp .pp-vbox{border:1px solid var(--ln);border-radius:12px;padding:26px;margin:0 0 22px;background:#fff;box-shadow:0 2px 10px rgba(13,34,51,.05)}.pp-pdp .pp-vbox h3{font-size:18px;margin:0 0 18px;padding-bottom:12px;border-bottom:2px solid var(--tl)}.pp-pdp .pp-vbox p{font-size:15px}.pp-pdp .pp-sub{font-size:12px;letter-spacing:1.5px;text-transform:uppercase;font-weight:800;color:var(--tl);margin:0 0 10px}.pp-pdp .pp-cta{display:inline-block;background:var(--gr);color:#fff!important;font-weight:800;font-size:15px;padding:15px 32px;border-radius:6px;text-decoration:none;margin-top:8px}.pp-pdp .pp-cta:hover{filter:brightness(1.08)}@media(max-width:900px){.pp-pdp .pp-tldr li{display:block}.pp-pdp .pp-tldr b{display:block;margin-bottom:2px}.pp-pdp .pp-vbox{padding:20px}.pp-pdp .pp-ov{padding:22px}}\u003c\/style\u003e\n\u003cdiv class=\"pp-pdp\"\u003e\n\u003csection class=\"pp-facts\" id=\"specs\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cdiv class=\"pp-fi\"\u003e\n\u003cb class=\"pp-v3\"\u003eCellular energy, repair and ageing\u003c\/b\u003e\u003cspan\u003eWhat it is used for\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-fi\"\u003e\n\u003cb class=\"pp-v2\"\u003e100mg daily, 5 on\/2 off\u003c\/b\u003e\u003cspan\u003eTypical dose\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-fi\"\u003e\n\u003cb class=\"pp-v2\"\u003eapprox 10 days per vial\u003c\/b\u003e\u003cspan\u003eOne vial lasts\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-fi\"\u003e\n\u003cb class=\"pp-v2\"\u003eIndependently HPLC tested\u003c\/b\u003e\u003cspan\u003eEvery batch\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec\" id=\"overview\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eOverview\u003c\/p\u003e\n\u003ch2\u003eIn plain English\u003c\/h2\u003e\n\u003cdiv class=\"pp-ov pp-prose\"\u003e\n\u003cp\u003eNAD+ is not a peptide. It is a molecule every cell in your body uses to turn food into usable energy, and to run its DNA repair and maintenance machinery.\u003c\/p\u003e\n\u003cp\u003eLevels fall with age. People use injectable NAD+ for energy, mental clarity, recovery and general longevity protocols. It is taken each morning, five days on and two days off — not in the evening, because it can interfere with sleep.\u003c\/p\u003e\n\u003cul class=\"pp-tldr\"\u003e\n\u003cli\u003e\n\u003cb\u003eWhat it is\u003c\/b\u003e\u003cspan\u003eA coenzyme central to energy production and DNA repair\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eMainly used for\u003c\/b\u003e\u003cspan\u003eEnergy, mental clarity, recovery, longevity protocols\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eTypical protocol\u003c\/b\u003e\u003cspan\u003e100mg daily, 5 days on \/ 2 off, for 8–16 weeks\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec pp-alt\" id=\"how\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cdiv class=\"pp-g2\"\u003e\n\u003cdiv class=\"pp-prose\"\u003e\n\u003cp class=\"pp-kick\"\u003eHow it works\u003c\/p\u003e\n\u003ch2\u003eWhat it actually does\u003c\/h2\u003e\n\u003cp\u003eNAD+ has two jobs, and mixing them up is the most common mistake made about it.\u003c\/p\u003e\n\u003cp\u003eThe first is energy. It shuttles electrons through the reactions that convert food into ATP, and it is recycled each time rather than used up.\u003c\/p\u003e\n\u003cp\u003eThe second is maintenance. A group of repair and signalling enzymes — including the sirtuins and the DNA-damage repair enzymes — physically consume NAD+ every time they act. That is where supply becomes the limit, and why levels falling with age matters.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-media\"\u003e\u003cimg class=\"pp-img\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0984\/2422\/6090\/files\/purist-nad.png?v=1785967535\" alt=\"NAD+ molecular structure and mechanism of action diagram\" width=\"1200\" height=\"1200\" decoding=\"async\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdetails class=\"pp-ac pp-more\"\u003e\u003csummary\u003eThe science in detail\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\n\u003cp\u003eNAD+ occupies two distinct roles in cell biology, and conflating them is the commonest error in describing it.\u003c\/p\u003e\n\u003cp\u003eThe first is catalytic. As the NAD+\/NADH couple it is the principal hydride acceptor of intermediary metabolism, cycling through several hundred dehydrogenase reactions: GAPDH in glycolysis, the isocitrate, α-ketoglutarate and malate dehydrogenases of the TCA cycle, and the dehydrogenase steps of β-oxidation. NADH then delivers electrons to complex I. In this role NAD+ is regenerated, not consumed, and the ratio of oxidised to reduced forms — rather than absolute quantity — sets the direction of flux. Phosphorylation by NAD kinase yields NADP+, whose reduced form NADPH drives reductive biosynthesis and regenerates glutathione and thioredoxin.\u003c\/p\u003e\n\u003cp\u003eThe second role is as a consumed substrate. Sirtuins (SIRT1–7) are NAD+-dependent deacylases: each turnover cleaves NAD+, releasing nicotinamide and 2'-O-acyl-ADP-ribose. PARP1 and PARP2 consume it heavily during poly-ADP-ribosylation in the DNA damage response. The ecto-enzymes CD38 and CD157 hydrolyse it to cyclic ADP-ribose, and SARM1 consumes it during axonal degeneration. Because these enzymes destroy the molecule, their activity is constrained by NAD+ availability — the basis for research linking NAD+ concentration to sirtuin signalling.\u003c\/p\u003e\n\u003cp\u003eSupply comes mainly from the salvage pathway, where NAMPT converts nicotinamide to NMN and the compartment-specific NMNAT isoforms adenylylate it to NAD+ in nucleus, cytosol and mitochondria. De novo synthesis from tryptophan via the kynurenine pathway and the Preiss-Handler route from nicotinic acid contribute less. Tissue NAD+ declines with age, with increased CD38 expression among the implicated mechanisms (Camacho-Pereira et al., Cell Metabolism, 2016).\u003c\/p\u003e\n\u003cp\u003eWhat distinguishes NAD+ from its precursors is transport. It is a large, doubly charged dinucleotide with poor membrane permeability, and extracellular NAD+ is substantially degraded by CD38 and CD73 to NMN and NR before uptake. Whether raising intracellular NAD+ is better served by the dinucleotide itself or by precursors remains an open question in the literature (Rajman, Chwalek and Sinclair, Cell Metabolism, 2018).\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/details\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eEvidence\u003c\/p\u003e\n\u003ch2\u003eWhat the research shows\u003c\/h2\u003e\n\u003cdiv class=\"pp-cards\"\u003e\n\u003cdiv class=\"pp-card\"\u003e\n\u003cspan class=\"pp-num\"\u003e01\u003c\/span\u003e\u003ch3\u003eTwo roles: fuel and maintenance\u003c\/h3\u003e\n\u003cp\u003eIt is recycled endlessly in energy production, but permanently consumed by repair and signalling enzymes.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-card\"\u003e\n\u003cspan class=\"pp-num\"\u003e02\u003c\/span\u003e\u003ch3\u003eRepair enzymes eat it\u003c\/h3\u003e\n\u003cp\u003eSirtuins and DNA-repair enzymes destroy NAD+ each time they work, so their activity is limited by how much is available.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-card\"\u003e\n\u003cspan class=\"pp-num\"\u003e03\u003c\/span\u003e\u003ch3\u003eTissue levels decline with age\u003c\/h3\u003e\n\u003cp\u003ePublished work links the decline partly to an enzyme that becomes more active as we get older.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-card\"\u003e\n\u003cspan class=\"pp-num\"\u003e04\u003c\/span\u003e\u003ch3\u003eInjection bypasses a real problem\u003c\/h3\u003e\n\u003cp\u003eNAD+ crosses cell membranes poorly and is broken down before it gets in, which is why route of delivery matters.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec pp-alt\" id=\"prep\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eMixing \u0026amp; dosage\u003c\/p\u003e\n\u003ch2\u003eHow to mix and dose it\u003c\/h2\u003e\n\u003cdiv class=\"pp-prose pp-wide\"\u003e\n\u003cp\u003eThese are the mixing and dosage instructions supplied by Purist Peptides and the manufacturer for this product.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eA 3ml vial of bacteriostatic water is included free with every peptide vial you order\u003c\/strong\u003e, so you have what you need to mix this on arrival.\u003c\/p\u003e\n\u003cdiv class=\"pp-vbox\"\u003e\n\u003ch3\u003eNAD+ 1000mg\u003c\/h3\u003e\n\u003cp class=\"pp-sub\"\u003eStep 1 — mix your vial\u003c\/p\u003e\n\u003col class=\"pp-step\"\u003e\n\u003cli\u003eDraw up 2ml of bacteriostatic water into a syringe\u003c\/li\u003e\n\u003cli\u003eWipe the rubber top of your vial with an alcohol swab and let it dry\u003c\/li\u003e\n\u003cli\u003eInsert the needle then slowly and carefully push the water down the inside wall of the vial — do not inject water straight onto the peptide powder\u003c\/li\u003e\n\u003cli\u003eGently roll the vial between your palms until the powder dissolves completely\u003c\/li\u003e\n\u003cli\u003eDo not shake\u003c\/li\u003e\n\u003cli\u003eAllow to settle in the fridge for 5–10 minutes. The liquid should look clear\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"pp-sub\"\u003eStep 2 — draw \u0026amp; inject your dose\u003c\/p\u003e\n\u003cp\u003eUse a 1ml insulin syringe to draw and inject your dose. A 1ml syringe = 100 units.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWith 2ml of water added, each 0.1ml (10 units) you draw = 50mg of NAD+.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"pp-dose\"\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eStage\u003c\/th\u003e\n\u003cth\u003eDose\u003c\/th\u003e\n\u003cth\u003eOn the syringe\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eStarting\u003c\/td\u003e\n\u003ctd\u003e50mg daily\u003c\/td\u003e\n\u003ctd\u003e10 units\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStandard\u003c\/td\u003e\n\u003ctd\u003e100mg daily\u003c\/td\u003e\n\u003ctd\u003e20 units\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003eVial duration at standard dose: approx 10 days\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhen to inject:\u003c\/strong\u003e Morning only. Do not inject in the evening — NAD+ activates sirtuin pathways that can interfere with sleep. 5 days on, 2 days off.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCycle length:\u003c\/strong\u003e 8 to 16 weeks.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp class=\"pp-sub\"\u003eHow to inject\u003c\/p\u003e\n\u003col class=\"pp-step\"\u003e\n\u003cli\u003eWipe your injection site with an alcohol swab and let it dry\u003c\/li\u003e\n\u003cli\u003ePinch a small fold of skin on your abdomen\u003c\/li\u003e\n\u003cli\u003eInsert the needle at a 45-degree angle into the pinched skin\u003c\/li\u003e\n\u003cli\u003eSlowly push the plunger down until empty\u003c\/li\u003e\n\u003cli\u003ePull the needle out and apply gentle pressure with the swab\u003c\/li\u003e\n\u003cli\u003eDispose of the needle safely in a sharps container — never recap or reuse\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"pp-sub\"\u003eStorage\u003c\/p\u003e\n\u003cp\u003eKeep refrigerated at 2 to 6 degrees Celsius at all times after mixing. Do not freeze. Protect from light and label the vial with the date you reconstituted it. Discard any solution that is hazy, discoloured or contains particles.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor informational purposes only. This is not medical advice. Speak to a qualified healthcare professional before starting any compound.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cfigure class=\"pp-fig\"\u003e\u003cimg class=\"pp-img\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0984\/2422\/6090\/files\/purist-reconstitution-steps-v2.png?v=1786504935\" alt=\"Four-step peptide reconstitution guide: bring the vial to room temperature, add bacteriostatic water down the vial wall, roll gently without shaking, and store refrigerated at 2 to 6 degrees Celsius without freezing\" width=\"1400\" height=\"900\" loading=\"lazy\" decoding=\"async\"\u003e\u003c\/figure\u003e\n\u003cp style=\"margin-top:26px\"\u003e\u003ca class=\"pp-cta\" href=\"#specs\" onclick=\"window.scrollTo({top:0,behavior:'smooth'});return false;\"\u003eReady to order — back to the top\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec pp-alt\" id=\"faq\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eQuestions\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003cdiv class=\"pp-faq\"\u003e\n\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eIs NAD+ a peptide?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eNo. It is a dinucleotide — nicotinamide mononucleotide joined to adenosine monophosphate through a pyrophosphate bridge. It is stocked alongside research peptides because it is handled and reconstituted in the same way, not because it belongs to the same chemical class.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eHow does NAD+ differ from NMN and NR?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eNMN and NR are biosynthetic precursors that enter the salvage pathway upstream of NAD+. Both are smaller and more readily transported. NAD+ itself is doubly charged and poorly membrane-permeant, and extracellular NAD+ is largely degraded to NMN and NR by CD38 and CD73 before it reaches the cell interior.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eWhat is it studied for?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eResearch contexts include mitochondrial function, sirtuin-dependent signalling, DNA repair capacity via PARP activity, and age-associated decline in tissue NAD+ concentration. Rajman, Chwalek and Sinclair (Cell Metabolism, 2018) review the in vivo evidence for NAD-boosting strategies.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eWhy is it less stable than the peptides you supply?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eThe nicotinamide-ribose glycosidic bond hydrolyses under alkaline conditions and degrades with heat and light. Lyophilised NAD+ is also strongly hygroscopic. Both properties argue for preparing solutions close to the point of use and keeping the dry powder sealed and desiccated.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eHow is purity verified?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eEvery batch is assayed by Bioindustrial Services in Boksburg, an independent biotechnology laboratory, using HPLC. We do not self-certify. The signed certificate of analysis for each batch — lab number, method and assayed result — is published on our \u003ca href=\"\/pages\/quality-standards\"\u003equality standards page\u003c\/a\u003e.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eHow long does delivery take?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eOrders are dispatched from the Netherlands with tracked courier delivery — 1–3 business days within the Netherlands, 2–5 business days to the rest of the EU. Full timelines are set out on our \u003ca href=\"\/pages\/delivery-process\"\u003edelivery process page\u003c\/a\u003e.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eCan I return an order?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eUnder the EU Consumer Rights Directive you may withdraw from your order within 14 days of delivery, without giving a reason, provided the vial's seal is intact. Vials that have been unsealed, opened, punctured or reconstituted cannot be returned, as sterility and integrity can no longer be assured (Article 16(e)). If your parcel arrives damaged, contact us within 48 hours with photographs of the packaging and product and we will arrange a replacement. The full terms are set out in our \u003ca href=\"\/pages\/return-refund-policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-links\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eExplore\u003c\/p\u003e\n\u003cdiv class=\"pp-chips\"\u003e\n\u003ca class=\"pp-chip pp-chip-lead\" href=\"\/collections\/anti-aging-longevity-peptides\"\u003eAlso in Anti-Ageing \u0026amp; Longevity\u003c\/a\u003e\u003ca class=\"pp-chip\" href=\"\/products\/mots-c\"\u003eMOTS-C\u003c\/a\u003e\u003ca class=\"pp-chip\" href=\"\/products\/glutathione\"\u003eGlutathione\u003c\/a\u003e\u003ca class=\"pp-chip\" href=\"\/products\/ghk-cu\"\u003eGHK-Cu\u003c\/a\u003e\u003ca class=\"pp-chip pp-chip-alt\" href=\"\/pages\/cellular-longevity-peptide-stack\"\u003eCellular Longevity Stack\u003c\/a\u003e\u003ca class=\"pp-chip pp-chip-alt\" href=\"\/pages\/peptide-stacks\"\u003eMetabolic Reset Stack\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003c\/div\u003e\n\u003cscript type=\"application\/ld+json\"\u003e{\"@context\":\"https:\/\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"Is NAD+ a peptide?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"No. It is a dinucleotide — nicotinamide mononucleotide joined to adenosine monophosphate through a pyrophosphate bridge. It is stocked alongside research peptides because it is handled and reconstituted in the same way, not because it belongs to the same chemical class.\"}},{\"@type\":\"Question\",\"name\":\"How does NAD+ differ from NMN and NR?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"NMN and NR are biosynthetic precursors that enter the salvage pathway upstream of NAD+. Both are smaller and more readily transported. NAD+ itself is doubly charged and poorly membrane-permeant, and extracellular NAD+ is largely degraded to NMN and NR by CD38 and CD73 before it reaches the cell interior.\"}},{\"@type\":\"Question\",\"name\":\"What is it studied for?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Research contexts include mitochondrial function, sirtuin-dependent signalling, DNA repair capacity via PARP activity, and age-associated decline in tissue NAD+ concentration. Rajman, Chwalek and Sinclair (Cell Metabolism, 2018) review the in vivo evidence for NAD-boosting strategies.\"}},{\"@type\":\"Question\",\"name\":\"Why is it less stable than the peptides you supply?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"The nicotinamide-ribose glycosidic bond hydrolyses under alkaline conditions and degrades with heat and light. Lyophilised NAD+ is also strongly hygroscopic. Both properties argue for preparing solutions close to the point of use and keeping the dry powder sealed and desiccated.\"}},{\"@type\":\"Question\",\"name\":\"How is purity verified?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Every batch is assayed by Bioindustrial Services in Boksburg, an independent biotechnology laboratory, using HPLC. We do not self-certify. The signed certificate of analysis for each batch — lab number, method and assayed result — is published on our quality standards page at \/pages\/quality-standards.\"}},{\"@type\":\"Question\",\"name\":\"How long does delivery take?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Orders are dispatched from the Netherlands with tracked courier delivery — 1–3 business days within the Netherlands, 2–5 business days to the rest of the EU. Full timelines are set out on our delivery process page at \/pages\/delivery-process.\"}},{\"@type\":\"Question\",\"name\":\"Can I return an order?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Under the EU Consumer Rights Directive you may withdraw from your order within 14 days of delivery, without giving a reason, provided the vial's seal is intact. Vials that have been unsealed, opened, punctured or reconstituted cannot be returned, as sterility and integrity can no longer be assured (Article 16(e)). If your parcel arrives damaged, contact us within 48 hours with photographs of the packaging and product and we will arrange a replacement. The full terms are set out at \/pages\/return-refund-policy.\"}}]}\u003c\/script\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":49172143669471,"sku":null,"price":79.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/8787\/3759\/files\/NAD_1.png?v=1778674618"}],"url":"https:\/\/puristpeptides.nl\/collections\/energy-mitochondrial-peptides.oembed","provider":"Purist Peptides NL","version":"1.0","type":"link"}