{"title":"Peptides for Hair Growth \u0026 Follicle Research","description":"\u003cstyle\u003eheader.purist-hero{display:none!important}.pp-intro{background:#fff!important;padding:0!important}.pp-intro .pp-wrap{max-width:none!important;margin:0!important;padding:0!important;text-align:left!important}.pp-intro .pp-kicker,.pp-intro .pp-trust{display:none!important}.pp-body{background:#fff!important;padding:0!important}.pp-body .pp-wrap{max-width:none!important;margin:0!important;padding:0!important}.pp-body .pp-cta,.pp-faqwrap:empty{display:none!important}.px-cut{display:none!important}\n.px{--nv:#0d2233;--tl:#3a9ab5;--ink:#1f2937;--mut:#5b6b7a;--ln:#e3e8ee;--sf:#f5f8fa;font-family:Montserrat,-apple-system,sans-serif;color:var(--ink);line-height:1.6}.px *{box-sizing:border-box}.px h1,.px h2,.px h3,.px h4{color:var(--nv)!important;font-weight:800;line-height:1.15;margin:0 0 14px;padding:0;border:0}.px p,.px li,.px td,.px th,.px div,.px span{color:var(--ink)}.px 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p{color:#5b6b7a!important;font-size:15px}.pp-body .px .px-ac summary h3{font-size:16.5px;font-weight:700;margin:0;display:inline}.pp-body .px a{border-bottom:0;font-weight:inherit}.pp-body .px .px-tbl td a,.pp-body .px .px-tbl td a:hover{color:#0d2233!important;font-weight:700;border-bottom:1px solid rgba(58,154,181,.5)}.pp-body .px .px-cbody .px-cd+.px-lnk{margin-top:auto}.pp-body .px .px-lnk,.pp-body .px .px-lnk:hover{border:1px solid #0d2233;color:#0d2233!important;font-weight:700}.pp-body .px .px-coa,.pp-body .px .px-coa:hover{border:1px solid #e3e8ee;color:#0d2233!important;font-weight:700}.pp-body .px .px-rel a,.pp-body .px .px-rel a:hover{border:1px solid #e3e8ee;color:#0d2233!important;font-weight:600}.pp-body .px .px-b2{border:1px solid #e3e8ee;color:#0d2233!important;font-weight:600}.pp-body .px .px-stkc,.pp-body .px .px-stkc:hover{border:1px solid #e3e8ee}.pp-body .px .px-stkc .px-stkt{color:#0d2233!important}.pp-body .px .px-stkc .px-stka{color:#3a9ab5!important}.pp-body .px ul,.pp-body .px ul li{background:none;border:0;padding:0;border-radius:0}.pp-body .px em{color:#5b6b7a;font-size:inherit}.pp-body .px .px-coa em{color:#3a9ab5!important;font-size:11px;font-weight:600}.pp-body .px .px-note em{font-size:12.5px}\n@media(max-width:1000px){.px-cc{grid-template-columns:repeat(2,1fr)}}@media(max-width:900px){.px-g2{grid-template-columns:1fr;gap:28px}.px-hero h1{font-size:30px}.px-stats .px-in{grid-template-columns:repeat(2,1fr);gap:20px}.px-sec{padding:42px 0}.px-sec h2,.pp-body .px .px-sec h2{font-size:23px}.px-tbl td:first-child{width:auto}}@media(max-width:560px){.px-cc,.px-cc1{grid-template-columns:1fr;max-width:none}.px-hero{padding:28px 0 36px}.px-hero h1{font-size:27px}}\n\u003c\/style\u003e\n\u003cdiv class=\"px px-top\"\u003e\n\u003cdiv class=\"px-full px-hero\"\u003e\u003cdiv class=\"px-in px-g2\"\u003e\n\u003cdiv\u003e\n\u003cdiv class=\"px-crumb\"\u003e\n\u003ca href=\"\/\"\u003eHome\u003c\/a\u003e\u003cspan\u003e\/\u003c\/span\u003e\u003ca href=\"\/collections\"\u003eCollections\u003c\/a\u003e\u003cspan\u003e\/\u003c\/span\u003eHair Growth\u003c\/div\u003e\n\u003cdiv class=\"px-kick\"\u003eHair Growth \u0026amp; Follicle Research\u003c\/div\u003e\n\u003ch1\u003ePeptides for Hair Growth \u0026amp; Follicle Research\u003c\/h1\u003e\n\u003cdiv class=\"px-lede\"\u003ePeptides for hair growth are compounds studied for follicle vascularisation, scalp integrity and the signalling that supports hair density. In the Purist range this research centres on a single compound — GHK-Cu, the copper-binding tripeptide with the deepest body of published work in follicle and scalp models.\u003c\/div\u003e\n\u003cul class=\"px-ticks\"\u003e\n\u003cli\u003e99%+ Verified Purity\u003c\/li\u003e\n\u003cli\u003eIndependent HPLC Assay\u003c\/li\u003e\n\u003cli\u003eThird-Party Lab Tested\u003c\/li\u003e\n\u003cli\u003eLyophilised \u0026amp; Sealed\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"px-btns\"\u003e\n\u003ca class=\"px-b1\" href=\"#px-grid\"\u003eView the 1 compound\u003c\/a\u003e\u003ca class=\"px-b2\" href=\"#px-choose\"\u003eHow to choose\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\u003cimg class=\"px-img\" alt=\"Purist Peptides research vials for hair growth research\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0984\/2422\/6090\/files\/Gemini_Generated_Image_6d5y8z6d5y8z6d5y_1.png?v=1772795583\u0026amp;width=900\" width=\"900\" height=\"900\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"px-full px-stats\"\u003e\u003cdiv class=\"px-in\"\u003e\n\u003cdiv\u003e\n\u003cb\u003e1\u003c\/b\u003e\u003ci\u003eCompound in category\u003c\/i\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cb\u003e99%+\u003c\/b\u003e\u003ci\u003eMinimum verified purity\u003c\/i\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cb\u003eHPLC\u003c\/b\u003e\u003ci\u003eIndependent assay method\u003c\/i\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cb\u003e100%\u003c\/b\u003e\u003ci\u003eBatches assayed\u003c\/i\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"px-cut\"\u003e\u003c\/p\u003e\n\u003cdiv class=\"px px-bot\"\u003e\n\u003cdiv class=\"px-full px-sec\"\u003e\u003cdiv class=\"px-in px-g2\"\u003e\n\u003cdiv\u003e\n\u003cdiv class=\"px-kick\"\u003eMechanisms\u003c\/div\u003e\n\u003ch2\u003eWhy hair research centres on copper peptides\u003c\/h2\u003e\n\u003cdiv class=\"px-lede\" style=\"max-width:none\"\u003eHair research approaches the follicle as a micro-organ dependent on its blood supply and surrounding matrix. GHK-Cu is studied for angiogenesis — the formation of new capillaries improving perifollicular blood supply — alongside collagen synthesis supporting the surrounding dermal structure, and anti-inflammatory signalling affecting the scalp micro-environment. That combination is why a single compound covers what would otherwise require several.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\u003cimg class=\"px-img\" alt=\"Purist Peptides research compounds in a laboratory setting\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0984\/2422\/6090\/files\/ChatGPT_Image_Mar_7_2026_11_45_56_AM.png?v=1772864180\u0026amp;width=800\" width=\"800\" height=\"800\" loading=\"lazy\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"px-full px-sec px-alt\"\u003e\u003cdiv class=\"px-in\"\u003e\n\u003cdiv class=\"px-kick\"\u003eStudy design\u003c\/div\u003e\n\u003ch2\u003eHow hair protocols differ from skin protocols\u003c\/h2\u003e\n\u003cdiv class=\"px-sub\" style=\"max-width:900px\"\u003eHair models typically use intradermal scalp administration rather than systemic subcutaneous dosing, at 500 mcg–1.5 mg, 3–5× weekly, over 8–12 weeks — a longer horizon than skin protocols because the hair cycle itself is slow, and follicle research endpoints take one to three months to become measurable. Excessive daily dosing is avoided to limit vascular overgrowth, and total exposure is kept under 3 mg per day. Unlike most compounds in the range, GHK-Cu does not require cycling, as it occurs naturally in plasma and does not cause receptor down-regulation.\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"px-full px-sec\"\u003e\u003cdiv class=\"px-in\"\u003e\n\u003cdiv class=\"px-kick\"\u003eThe range\u003c\/div\u003e\n\u003ch2\u003eCompounds in this category\u003c\/h2\u003e\n\u003cdiv class=\"px-sub\"\u003eThe compounds grouped here, each with the pathway it is studied for and the protocol shape most often used.\u003c\/div\u003e\n\u003cdiv class=\"px-cc px-cc1\"\u003e\u003cdiv class=\"px-card\"\u003e\n\u003ca href=\"\/products\/ghk-cu\"\u003e\u003cimg alt=\"GHK-Cu research peptide vial by Purist Peptides\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0984\/2422\/6090\/files\/purist-peptides-ghk-cu-skin-collagen-hair-anti-aging-vial.jpg?v=1784719614\u0026amp;width=520\" width=\"520\" height=\"520\" loading=\"lazy\"\u003e\u003c\/a\u003e\u003cdiv class=\"px-cbody\"\u003e\n\u003ch4\u003eGHK-Cu\u003c\/h4\u003e\n\u003cdiv class=\"px-mech\"\u003eCopper tripeptide\u003c\/div\u003e\n\u003cdiv class=\"px-cd\"\u003eA copper-binding tripeptide studied for follicle vascularisation, scalp integrity, collagen support and hair density. Published third-party test report available (100 mg). Hair protocols typically run 500 mcg–1.5 mg intradermally, 3–5× weekly for 8–12 weeks, with a documented 3 mg daily ceiling\u003c\/div\u003e\n\u003ca class=\"px-lnk\" href=\"\/products\/ghk-cu\"\u003eView GHK-Cu\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"px-full px-sec px-alt\" id=\"px-choose\"\u003e\u003cdiv class=\"px-in\"\u003e\n\u003cdiv class=\"px-kick\"\u003eSelection\u003c\/div\u003e\n\u003ch2\u003eHow to choose\u003c\/h2\u003e\n\u003cdiv class=\"px-sub\"\u003eStart from the research question, not the compound name.\u003c\/div\u003e\n\u003ctable class=\"px-tbl\"\u003e\n\u003ctr\u003e\n\u003cth\u003eIf the research question is…\u003c\/th\u003e\n\u003cth\u003eStart with\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFollicle and scalp research\u003c\/td\u003e\n\u003ctd\u003eGHK-Cu, the only compound in the range with an established hair-model literature\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eResearching skin and hair together\u003c\/td\u003e\n\u003ctd\u003eGHK-Cu covers both; see \u003ca href=\"\/collections\/skin-peptides\"\u003ePeptides for Skin\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWant GHK-Cu combined with repair peptides\u003c\/td\u003e\n\u003ctd\u003e\n\u003ca href=\"\/products\/glow\"\u003eGLOW\u003c\/a\u003e and \u003ca href=\"\/products\/klow\"\u003eKLOW\u003c\/a\u003e both contain it\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBroader anti-aging context\u003c\/td\u003e\n\u003ctd\u003e\u003ca href=\"\/collections\/anti-aging-longevity-peptides\"\u003eAnti-Aging \u0026amp; Longevity\u003c\/a\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"px-full px-sec px-alt\"\u003e\u003cdiv class=\"px-in px-g2\"\u003e\n\u003cdiv\u003e\u003cimg class=\"px-img\" alt=\"Independent laboratory testing of Purist Peptides research compounds\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0984\/2422\/6090\/files\/ChatGPT_Image_Mar_7_2026_01_51_37_PM.png?v=1772871717\u0026amp;width=800\" width=\"800\" height=\"800\" loading=\"lazy\"\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cdiv class=\"px-kick\"\u003eVerified quality\u003c\/div\u003e\n\u003ch2\u003eTested before it ships\u003c\/h2\u003e\n\u003cdiv class=\"px-sub\"\u003ePublished third-party test report for GHK-Cu (100 mg) · minimum 99% verified purity · documented copper-load safety guidance, maximum daily exposure and intradermal protocol detail on the product page · lyophilised, refrigerate 2–8 °C after reconstitution. See Quality Standards.\u003c\/div\u003e\n\u003cdiv class=\"px-btns\"\u003e\u003ca class=\"px-b2\" href=\"\/pages\/quality-standards\"\u003eSee Quality Standards \u0026amp; all COAs\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"px-full px-sec\"\u003e\u003cdiv class=\"px-in\"\u003e\u003cdiv class=\"px-faq\"\u003e\n\u003cdiv class=\"px-kick\"\u003eQuestions\u003c\/div\u003e\n\u003ch2\u003eHair Growth research FAQ\u003c\/h2\u003e\n\u003cdetails class=\"px-ac\" open\u003e\u003csummary\u003e\u003ch3\u003eWhat is GHK-Cu studied for in hair research?\u003c\/h3\u003e\u003c\/summary\u003e\u003cdiv class=\"px-ab\"\u003e\u003cp\u003eGHK-Cu is referenced for perifollicular angiogenesis — improving the capillary supply to the follicle — alongside collagen support for surrounding dermal structure and anti-inflammatory signalling in the scalp micro-environment.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"px-ac\"\u003e\u003csummary\u003e\u003ch3\u003eHow is GHK-Cu administered in hair protocols?\u003c\/h3\u003e\u003c\/summary\u003e\u003cdiv class=\"px-ab\"\u003e\u003cp\u003eHair models typically use intradermal scalp administration rather than systemic subcutaneous dosing, at 500 mcg–1.5 mg, 3–5× weekly. Full reconstitution and syringe guidance is on the product page.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"px-ac\"\u003e\u003csummary\u003e\u003ch3\u003eHow long before hair research endpoints are measurable?\u003c\/h3\u003e\u003c\/summary\u003e\u003cdiv class=\"px-ab\"\u003e\u003cp\u003eProtocols generally run 8–12 weeks, because the hair growth cycle is slow and follicle-level changes take one to three months to register. This is a longer horizon than skin protocols using the same compound.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"px-ac\"\u003e\u003csummary\u003e\u003ch3\u003eIs there a maximum safe exposure?\u003c\/h3\u003e\u003c\/summary\u003e\u003cdiv class=\"px-ab\"\u003e\u003cp\u003eResearch guidance caps daily exposure at 3 mg. Sustained exposure above that, particularly alongside copper supplementation, raises copper-accumulation concerns — documented in full on the GHK-Cu product page.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"px-ac\"\u003e\u003csummary\u003e\u003ch3\u003eDoes GHK-Cu need to be cycled?\u003c\/h3\u003e\u003c\/summary\u003e\u003cdiv class=\"px-ab\"\u003e\u003cp\u003eNo. It occurs naturally in human plasma and does not cause receptor down-regulation, so protocols commonly run continuously for 3–6 months rather than in on\/off cycles.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\n\u003c\/div\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"px-full px-sec px-alt\"\u003e\u003cdiv class=\"px-in\"\u003e\n\u003cdiv class=\"px-kick\"\u003eKeep exploring\u003c\/div\u003e\n\u003ch2\u003eRelated research categories\u003c\/h2\u003e\n\u003cdiv class=\"px-rel\"\u003e\n\u003ca href=\"\/collections\/skin-peptides\"\u003eSkin \u0026amp; Collagen\u003c\/a\u003e\u003ca href=\"\/collections\/anti-aging-longevity-peptides\"\u003eAnti-Ageing \u0026amp; Longevity\u003c\/a\u003e\u003ca href=\"\/collections\/recovery-repair-peptides\"\u003eRecovery \u0026amp; Repair\u003c\/a\u003e\u003ca href=\"\/collections\/energy-mitochondrial-peptides\"\u003eEnergy \u0026amp; Mitochondrial\u003c\/a\u003e\u003ca href=\"\/collections\/all-peptides\"\u003eThe full range\u003c\/a\u003e\u003ca href=\"\/pages\/peptide-stacks\"\u003eAll peptide stacks\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"px-full px-cta\"\u003e\u003cdiv class=\"px-in\"\u003e\n\u003ch2\u003eResearch-grade, verified, traceable.\u003c\/h2\u003e\n\u003cp\u003eEvery batch assayed by an independent laboratory before release — minimum 99% verified purity.\u003c\/p\u003e\n\u003cdiv class=\"px-btns\" style=\"justify-content:center\"\u003e\n\u003ca class=\"px-b1\" style=\"background:#fff;color:#0d2233!important\" href=\"#px-grid\"\u003eShop this category\u003c\/a\u003e\u003ca class=\"px-b2\" style=\"background:transparent;color:#fff!important;border:1px solid rgba(255,255,255,.35)\" href=\"\/pages\/quality-standards\"\u003eQuality Standards\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"px-full px-note\"\u003e\u003cdiv class=\"px-in\"\u003e\u003cem\u003eResearch use only. Not for human or veterinary consumption. Supplied strictly for qualified researchers and laboratory settings.\u003c\/em\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cscript\u003e\n(function(){var th=document.querySelector('header.purist-hero h1');if(th)th.remove();var g=document.querySelector('[id*=\"collection_products\"]');if(g\u0026\u0026!document.getElementById('px-grid')){var a=document.createElement('span');a.id='px-grid';a.style.cssText='display:block;position:relative;top:-90px';g.parentNode.insertBefore(a,g);}})();\n\u003c\/script\u003e","products":[{"product_id":"ghk-cu","title":"GHK-CU","description":"\u003cstyle\u003e.pp-pdp{--nv:#0d2233;--tl:#3a9ab5;--ink:#1f2937;--mut:#5b6b7a;--ln:#e3e8ee;--sf:#f5f8fa;--gr:#1E9E5A;font-family:Montserrat,-apple-system,sans-serif;color:var(--ink);line-height:1.6;margin:34px 0 0;width:100%;max-width:100%;overflow-x:hidden;background:#fff;text-align:left}.pp-pdp *{box-sizing:border-box}.pp-pdp h2,.pp-pdp 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.pp-step{counter-reset:s;list-style:none;padding:0;margin:0 0 18px}.pp-pdp .pp-step li{position:relative;padding:0 0 11px 34px;font-size:15px;color:var(--mut)}.pp-pdp .pp-step li:before{counter-increment:s;content:counter(s);position:absolute;left:0;top:1px;width:22px;height:22px;border-radius:50%;background:var(--tl);color:#fff;font-size:12px;font-weight:800;display:flex;align-items:center;justify-content:center}.pp-pdp .pp-warn{background:#fff6e5;border-left:4px solid #e0a33a;padding:13px 18px;border-radius:0 8px 8px 0;font-size:14.5px;color:var(--ink);margin:0 0 16px}.pp-pdp .pp-warn p{margin:0 0 6px;font-size:14.5px}.pp-pdp .pp-warn p:last-child{margin:0}.pp-pdp .pp-vbox{border:1px solid var(--ln);border-radius:12px;padding:26px;margin:0 0 22px;background:#fff;box-shadow:0 2px 10px rgba(13,34,51,.05)}.pp-pdp .pp-vbox h3{font-size:18px;margin:0 0 18px;padding-bottom:12px;border-bottom:2px solid var(--tl)}.pp-pdp .pp-vbox p{font-size:15px}.pp-pdp .pp-sub{font-size:12px;letter-spacing:1.5px;text-transform:uppercase;font-weight:800;color:var(--tl);margin:0 0 10px}.pp-pdp .pp-cta{display:inline-block;background:var(--gr);color:#fff!important;font-weight:800;font-size:15px;padding:15px 32px;border-radius:6px;text-decoration:none;margin-top:8px}.pp-pdp .pp-cta:hover{filter:brightness(1.08)}@media(max-width:900px){.pp-pdp .pp-tldr li{display:block}.pp-pdp .pp-tldr b{display:block;margin-bottom:2px}.pp-pdp .pp-vbox{padding:20px}.pp-pdp .pp-ov{padding:22px}}\u003c\/style\u003e\n\u003cdiv class=\"pp-pdp\"\u003e\n\u003csection class=\"pp-facts\" id=\"specs\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cdiv class=\"pp-fi\"\u003e\n\u003cb class=\"pp-v3\"\u003eSkin firmness, tone and repair\u003c\/b\u003e\u003cspan\u003eWhat it is used for\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-fi\"\u003e\n\u003cb class=\"pp-v2\"\u003e2mg daily\u003c\/b\u003e\u003cspan\u003eTypical dose\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-fi\"\u003e\n\u003cb class=\"pp-v2\"\u003e50 days per vial\u003c\/b\u003e\u003cspan\u003eOne vial lasts\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-fi\"\u003e\n\u003cb class=\"pp-v2\"\u003eIndependently HPLC tested\u003c\/b\u003e\u003cspan\u003eEvery batch\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec\" id=\"overview\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eOverview\u003c\/p\u003e\n\u003ch2\u003eIn plain English\u003c\/h2\u003e\n\u003cdiv class=\"pp-ov pp-prose\"\u003e\n\u003cp\u003eGHK-Cu is a very short peptide — three amino acids — bound to copper. Your body makes it naturally, and levels drop substantially with age. That decline is what first made it interesting.\u003c\/p\u003e\n\u003cp\u003eIt is the best-known peptide for skin: firmness, tone, texture and scarring. It is also used for hair and general tissue repair.\u003c\/p\u003e\n\u003cul class=\"pp-tldr\"\u003e\n\u003cli\u003e\n\u003cb\u003eWhat it is\u003c\/b\u003e\u003cspan\u003eA copper-bound tripeptide (Gly-His-Lys) the body produces naturally\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eMainly used for\u003c\/b\u003e\u003cspan\u003eSkin firmness and tone, scarring, hair, tissue repair\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eTypical protocol\u003c\/b\u003e\u003cspan\u003e2mg once daily, morning, for 8–12 weeks\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec pp-alt\" id=\"how\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cdiv class=\"pp-g2\"\u003e\n\u003cdiv class=\"pp-prose\"\u003e\n\u003cp class=\"pp-kick\"\u003eHow it works\u003c\/p\u003e\n\u003ch2\u003eWhat it actually does\u003c\/h2\u003e\n\u003cp\u003eCopper is not optional for skin structure. The enzyme that cross-links collagen and elastin into mature, springy fibres cannot work without it.\u003c\/p\u003e\n\u003cp\u003eGHK-Cu's job is delivery. It picks copper up from blood proteins and hands it over to the cells and enzymes that need it — it does not lock it away.\u003c\/p\u003e\n\u003cp\u003eThat is the difference between GHK-Cu and either a copper supplement or a copper-free peptide. It also influences a wide set of genes involved in matrix turnover and antioxidant defence.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-media\"\u003e\u003cimg class=\"pp-img\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0984\/2422\/6090\/files\/purist-ghk-cu.png?v=1785967535\" alt=\"GHK-Cu molecular structure and mechanism of action diagram\" width=\"1200\" height=\"1200\" decoding=\"async\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdetails class=\"pp-ac pp-more\"\u003e\u003csummary\u003eThe science in detail\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\n\u003cp\u003eGHK is a tripeptide — glycine, histidine, lysine — isolated from human plasma by Pickart and colleagues in the early 1970s and later identified as a fragment released during proteolysis of collagen and other matrix proteins. Its plasma concentration falls substantially with age, the observation that first prompted interest in it as an endogenous repair signal.\u003c\/p\u003e\n\u003cp\u003eThe chemistry that defines it is copper coordination. The N-terminal amine, the deprotonated amide nitrogen of the first peptide bond and the imidazole nitrogen of histidine form a square-planar chelation site for Cu2+ with very high affinity — comparable to the copper-binding site of serum albumin. GHK therefore does not sequester copper inertly; it exchanges it, accepting Cu2+ from albumin and delivering it to cellular transporters and cuproenzymes. That is why the complex behaves differently from either free copper salts or a copper-free peptide.\u003c\/p\u003e\n\u003cp\u003eThe delivery role connects directly to matrix biology. Lysyl oxidase, the enzyme that cross-links collagen and elastin fibrils into mature load-bearing structures, is copper-dependent; so are superoxide dismutase 1 and cytochrome c oxidase. Copper availability is therefore rate-limiting for matrix maturation rather than merely for matrix synthesis — the distinction between GHK-Cu and peptides that stimulate collagen transcription alone.\u003c\/p\u003e\n\u003cp\u003eBeyond copper transport, GHK-Cu shows broad transcriptional activity. Pickart and Margolina (Int J Mol Sci, 2018), drawing on Broad Institute Connectivity Map data, reported modulation of expression across a large fraction of human genes, with the pattern favouring tissue remodelling: increased collagen I, decorin and other small proteoglycans, alongside coordinated changes in matrix metalloproteinases and their TIMP inhibitors. That combination is characteristic of controlled turnover rather than simple accumulation. Pickart, Vasquez-Soltero and Margolina (BioMed Research International, 2015) reviewed the same pathways in skin regeneration, including antioxidant and anti-inflammatory gene modulation.\u003c\/p\u003e\n\u003cp\u003eAmong the skin-directed compounds on this site, GHK-Cu occupies the copper and matrix-maturation position. BPC-157 and TB-500, its partners in the GLOW and KLOW blends, act on angiogenesis and actin dynamics — adjacent but mechanistically separate.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/details\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eEvidence\u003c\/p\u003e\n\u003ch2\u003eWhat the research shows\u003c\/h2\u003e\n\u003cdiv class=\"pp-cards\"\u003e\n\u003cdiv class=\"pp-card\"\u003e\n\u003cspan class=\"pp-num\"\u003e01\u003c\/span\u003e\u003ch3\u003eYour natural level falls with age\u003c\/h3\u003e\n\u003cp\u003eGHK is present in human plasma and declines substantially over the decades — the original reason for research interest.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-card\"\u003e\n\u003cspan class=\"pp-num\"\u003e02\u003c\/span\u003e\u003ch3\u003eDelivers copper rather than storing it\u003c\/h3\u003e\n\u003cp\u003eIt binds copper about as tightly as your blood's main carrier protein, then releases it to cells.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-card\"\u003e\n\u003cspan class=\"pp-num\"\u003e03\u003c\/span\u003e\u003ch3\u003eSupports collagen cross-linking\u003c\/h3\u003e\n\u003cp\u003eThe enzyme that turns new collagen and elastin into mature fibre is copper-dependent.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-card\"\u003e\n\u003cspan class=\"pp-num\"\u003e04\u003c\/span\u003e\u003ch3\u003eBroad effect on repair genes\u003c\/h3\u003e\n\u003cp\u003ePublished gene-expression work reports it shifts a wide set of matrix and antioxidant genes toward controlled repair.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec pp-alt\" id=\"prep\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eMixing \u0026amp; dosage\u003c\/p\u003e\n\u003ch2\u003eHow to mix and dose it\u003c\/h2\u003e\n\u003cdiv class=\"pp-prose pp-wide\"\u003e\n\u003cp\u003eThese are the mixing and dosage instructions supplied by Purist Peptides and the manufacturer for this product.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eA 3ml vial of bacteriostatic water is included free with every peptide vial you order\u003c\/strong\u003e, so you have what you need to mix this on arrival.\u003c\/p\u003e\n\u003cdiv class=\"pp-vbox\"\u003e\n\u003ch3\u003eGHK-Cu 100mg\u003c\/h3\u003e\n\u003cp class=\"pp-sub\"\u003eStep 1 — mix your vial\u003c\/p\u003e\n\u003col class=\"pp-step\"\u003e\n\u003cli\u003eDraw up 2ml of bacteriostatic water into a syringe\u003c\/li\u003e\n\u003cli\u003eWipe the rubber top of your vial with an alcohol swab and let it dry\u003c\/li\u003e\n\u003cli\u003eInsert the needle then slowly and carefully push the water down the inside wall of the vial — do not inject water straight onto the peptide powder\u003c\/li\u003e\n\u003cli\u003eGently roll the vial between your palms until the powder dissolves completely\u003c\/li\u003e\n\u003cli\u003eDo not shake\u003c\/li\u003e\n\u003cli\u003eAllow to settle in the fridge for 5–10 minutes. The liquid should look clear\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"pp-sub\"\u003eStep 2 — draw \u0026amp; inject your dose\u003c\/p\u003e\n\u003cp\u003eUse a 1ml insulin syringe to draw and inject your dose. A 1ml syringe = 100 units.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWith 2ml of water added, each 0.1ml (10 units) you draw = 5mg of GHK-Cu.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"pp-dose\"\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eStage\u003c\/th\u003e\n\u003cth\u003eDose\u003c\/th\u003e\n\u003cth\u003eOn the syringe\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eStarting\u003c\/td\u003e\n\u003ctd\u003e1mg daily\u003c\/td\u003e\n\u003ctd\u003e2 units\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStandard\u003c\/td\u003e\n\u003ctd\u003e2mg daily\u003c\/td\u003e\n\u003ctd\u003e4 units\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003eVial duration at standard dose: 50 days\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhen to inject:\u003c\/strong\u003e Once daily, morning preferred.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCycle length:\u003c\/strong\u003e 8 to 12 weeks, then reassess.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp class=\"pp-sub\"\u003eHow to inject\u003c\/p\u003e\n\u003col class=\"pp-step\"\u003e\n\u003cli\u003eWipe your injection site with an alcohol swab and let it dry\u003c\/li\u003e\n\u003cli\u003ePinch a small fold of skin on your abdomen\u003c\/li\u003e\n\u003cli\u003eInsert the needle at a 45-degree angle into the pinched skin\u003c\/li\u003e\n\u003cli\u003eSlowly push the plunger down until empty\u003c\/li\u003e\n\u003cli\u003ePull the needle out and apply gentle pressure with the swab\u003c\/li\u003e\n\u003cli\u003eDispose of the needle safely in a sharps container — never recap or reuse\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"pp-sub\"\u003eStorage\u003c\/p\u003e\n\u003cp\u003eKeep refrigerated at 2 to 6 degrees Celsius at all times after mixing. Do not freeze. Protect from light and label the vial with the date you reconstituted it. Discard any solution that is hazy, discoloured or contains particles.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor informational purposes only. This is not medical advice. Speak to a qualified healthcare professional before starting any compound.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cfigure class=\"pp-fig\"\u003e\u003cimg class=\"pp-img\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0984\/2422\/6090\/files\/purist-reconstitution-steps-v2.png?v=1786504935\" alt=\"Four-step peptide reconstitution guide: bring the vial to room temperature, add bacteriostatic water down the vial wall, roll gently without shaking, and store refrigerated at 2 to 6 degrees Celsius without freezing\" width=\"1400\" height=\"900\" loading=\"lazy\" decoding=\"async\"\u003e\u003c\/figure\u003e\n\u003cp style=\"margin-top:26px\"\u003e\u003ca class=\"pp-cta\" href=\"#specs\" onclick=\"window.scrollTo({top:0,behavior:'smooth'});return false;\"\u003eReady to order — back to the top\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec pp-alt\" id=\"faq\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eQuestions\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003cdiv class=\"pp-faq\"\u003e\n\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eWhy is the copper part significant?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eBecause the peptide's principal characterised function is copper transport. GHK binds Cu2+ tightly enough to accept it from albumin but reversibly enough to pass it on to cellular transporters and copper-dependent enzymes. A copper-free GHK preparation is a different research material with a different activity profile.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eWhy is the reconstituted solution blue?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eThe colour comes from d-d electronic transitions of the coordinated copper(II) ion. It is expected, and its presence is a rough indication that the complex remains intact. Loss of colour or a marked colour shift suggests dissociation or degradation.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eHow does GHK-Cu differ from BPC-157 and TB-500?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eDifferent mechanisms entirely. GHK-Cu delivers copper to matrix enzymes and modulates matrix gene expression. BPC-157 is studied chiefly for angiogenic and growth factor signalling; TB-500 for actin sequestration and cell migration. They appear together in the GLOW and KLOW blends because the pathways are complementary rather than overlapping.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eWhat is it studied for?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003ePublished research centres on extracellular matrix remodelling, wound and tissue repair models, antioxidant and anti-inflammatory gene expression, and dermatological applications. Pickart's laboratory produced the majority of the foundational literature.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eHow is purity verified?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eEvery batch is assayed by Bioindustrial Services in Boksburg, an independent biotechnology laboratory, using HPLC. We do not self-certify. The signed certificate of analysis for each batch — lab number, method and assayed result — is published on our \u003ca href=\"\/pages\/quality-standards\"\u003equality standards page\u003c\/a\u003e.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eHow long does delivery take?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eOrders are dispatched from the Netherlands with tracked courier delivery — 1–3 business days within the Netherlands, 2–5 business days to the rest of the EU. Full timelines are set out on our \u003ca href=\"\/pages\/delivery-process\"\u003edelivery process page\u003c\/a\u003e.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eCan I return an order?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eUnder the EU Consumer Rights Directive you may withdraw from your order within 14 days of delivery, without giving a reason, provided the vial's seal is intact. Vials that have been unsealed, opened, punctured or reconstituted cannot be returned, as sterility and integrity can no longer be assured (Article 16(e)). If your parcel arrives damaged, contact us within 48 hours with photographs of the packaging and product and we will arrange a replacement. The full terms are set out in our \u003ca href=\"\/pages\/return-refund-policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-links\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eExplore\u003c\/p\u003e\n\u003cdiv class=\"pp-chips\"\u003e\n\u003ca class=\"pp-chip pp-chip-lead\" href=\"\/collections\/skin-peptides\"\u003eAlso in Skin, Collagen \u0026amp; Cellular Renewal\u003c\/a\u003e\u003ca class=\"pp-chip\" href=\"\/products\/glow\"\u003eGLOW\u003c\/a\u003e\u003ca class=\"pp-chip\" href=\"\/products\/klow\"\u003eKLOW\u003c\/a\u003e\u003ca class=\"pp-chip\" href=\"\/products\/glutathione\"\u003eGlutathione\u003c\/a\u003e\u003ca class=\"pp-chip pp-chip-alt\" href=\"\/pages\/peptide-stacks\"\u003eSkin Recovery Stack\u003c\/a\u003e\u003ca class=\"pp-chip pp-chip-alt\" href=\"\/pages\/peptide-stacks\"\u003eSkin \u0026amp; Anti-Ageing Stack\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003c\/div\u003e\n\u003cscript type=\"application\/ld+json\"\u003e{\"@context\":\"https:\/\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"Why is the copper part significant?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Because the peptide's principal characterised function is copper transport. GHK binds Cu2+ tightly enough to accept it from albumin but reversibly enough to pass it on to cellular transporters and copper-dependent enzymes. A copper-free GHK preparation is a different research material with a different activity profile.\"}},{\"@type\":\"Question\",\"name\":\"Why is the reconstituted solution blue?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"The colour comes from d-d electronic transitions of the coordinated copper(II) ion. It is expected, and its presence is a rough indication that the complex remains intact. Loss of colour or a marked colour shift suggests dissociation or degradation.\"}},{\"@type\":\"Question\",\"name\":\"How does GHK-Cu differ from BPC-157 and TB-500?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Different mechanisms entirely. GHK-Cu delivers copper to matrix enzymes and modulates matrix gene expression. BPC-157 is studied chiefly for angiogenic and growth factor signalling; TB-500 for actin sequestration and cell migration. They appear together in the GLOW and KLOW blends because the pathways are complementary rather than overlapping.\"}},{\"@type\":\"Question\",\"name\":\"What is it studied for?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Published research centres on extracellular matrix remodelling, wound and tissue repair models, antioxidant and anti-inflammatory gene expression, and dermatological applications. Pickart's laboratory produced the majority of the foundational literature.\"}},{\"@type\":\"Question\",\"name\":\"How is purity verified?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Every batch is assayed by Bioindustrial Services in Boksburg, an independent biotechnology laboratory, using HPLC. We do not self-certify. The signed certificate of analysis for each batch — lab number, method and assayed result — is published on our quality standards page at \/pages\/quality-standards.\"}},{\"@type\":\"Question\",\"name\":\"How long does delivery take?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Orders are dispatched from the Netherlands with tracked courier delivery — 1–3 business days within the Netherlands, 2–5 business days to the rest of the EU. Full timelines are set out on our delivery process page at \/pages\/delivery-process.\"}},{\"@type\":\"Question\",\"name\":\"Can I return an order?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Under the EU Consumer Rights Directive you may withdraw from your order within 14 days of delivery, without giving a reason, provided the vial's seal is intact. Vials that have been unsealed, opened, punctured or reconstituted cannot be returned, as sterility and integrity can no longer be assured (Article 16(e)). If your parcel arrives damaged, contact us within 48 hours with photographs of the packaging and product and we will arrange a replacement. The full terms are set out at \/pages\/return-refund-policy.\"}}]}\u003c\/script\u003e","brand":"Purist Peptides","offers":[{"title":"Default Title","offer_id":49172132004063,"sku":null,"price":54.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/8787\/3759\/files\/purist-peptides-ghk-cu-skin-collagen-hair-anti-aging-vial.jpg?v=1789217635"}],"url":"https:\/\/puristpeptides.nl\/collections\/hair-growth-peptides.oembed","provider":"Purist Peptides NL","version":"1.0","type":"link"}