{"product_id":"hcg","title":"HCG","description":"\u003cstyle\u003e.pp-pdp{--nv:#0d2233;--tl:#3a9ab5;--ink:#1f2937;--mut:#5b6b7a;--ln:#e3e8ee;--sf:#f5f8fa;--gr:#1E9E5A;font-family:Montserrat,-apple-system,sans-serif;color:var(--ink);line-height:1.6;margin:34px 0 0;width:100%;max-width:100%;overflow-x:hidden;background:#fff;text-align:left}.pp-pdp *{box-sizing:border-box}.pp-pdp h2,.pp-pdp h3{color:var(--nv);font-weight:800;line-height:1.15;margin:0 0 14px}.pp-pdp p{color:var(--ink);margin:0 0 14px}.pp-pdp p:last-child{margin-bottom:0}.pp-pdp a{color:#0d6c8a}.pp-pdp .pp-in{max-width:1180px;margin:0 auto;padding:0 24px}.pp-pdp .pp-kick{color:var(--tl);font-size:12px;letter-spacing:2.16px;text-transform:uppercase;font-weight:600;margin:0 0 12px}.pp-pdp .pp-sec{padding:56px 0}.pp-pdp .pp-alt{background:var(--sf)}.pp-pdp .pp-sec h2{font-size:30px}.pp-pdp .pp-prose p{font-size:15.5px;color:var(--mut)}.pp-pdp .pp-prose p strong{color:var(--nv)}.pp-pdp .pp-wide{max-width:900px}.pp-pdp 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td{text-align:left;padding:11px 14px;border-bottom:1px solid var(--ln);font-size:14.5px;color:var(--mut)}.pp-pdp .pp-dose th{background:var(--nv);color:#fff;font-size:11.5px;letter-spacing:1.2px;text-transform:uppercase;font-weight:700}.pp-pdp .pp-dose td:first-child{font-weight:700;color:var(--nv);white-space:nowrap}.pp-pdp .pp-step{counter-reset:s;list-style:none;padding:0;margin:0 0 18px}.pp-pdp .pp-step li{position:relative;padding:0 0 11px 34px;font-size:15px;color:var(--mut)}.pp-pdp .pp-step li:before{counter-increment:s;content:counter(s);position:absolute;left:0;top:1px;width:22px;height:22px;border-radius:50%;background:var(--tl);color:#fff;font-size:12px;font-weight:800;display:flex;align-items:center;justify-content:center}.pp-pdp .pp-warn{background:#fff6e5;border-left:4px solid #e0a33a;padding:13px 18px;border-radius:0 8px 8px 0;font-size:14.5px;color:var(--ink);margin:0 0 16px}.pp-pdp .pp-warn p{margin:0 0 6px;font-size:14.5px}.pp-pdp .pp-warn p:last-child{margin:0}.pp-pdp .pp-vbox{border:1px solid var(--ln);border-radius:12px;padding:26px;margin:0 0 22px;background:#fff;box-shadow:0 2px 10px rgba(13,34,51,.05)}.pp-pdp .pp-vbox h3{font-size:18px;margin:0 0 18px;padding-bottom:12px;border-bottom:2px solid var(--tl)}.pp-pdp .pp-vbox p{font-size:15px}.pp-pdp .pp-sub{font-size:12px;letter-spacing:1.5px;text-transform:uppercase;font-weight:800;color:var(--tl);margin:0 0 10px}.pp-pdp .pp-cta{display:inline-block;background:var(--gr);color:#fff!important;font-weight:800;font-size:15px;padding:15px 32px;border-radius:6px;text-decoration:none;margin-top:8px}.pp-pdp .pp-cta:hover{filter:brightness(1.08)}@media(max-width:900px){.pp-pdp .pp-tldr li{display:block}.pp-pdp .pp-tldr b{display:block;margin-bottom:2px}.pp-pdp .pp-vbox{padding:20px}.pp-pdp .pp-ov{padding:22px}}\u003c\/style\u003e\n\u003cdiv class=\"pp-pdp\"\u003e\n\u003csection class=\"pp-facts\" id=\"specs\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cdiv class=\"pp-fi\"\u003e\n\u003cb class=\"pp-v3\"\u003eMaintaining natural testosterone production\u003c\/b\u003e\u003cspan\u003eWhat it is used for\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-fi\"\u003e\n\u003cb class=\"pp-v2\"\u003e250iu daily\u003c\/b\u003e\u003cspan\u003eTypical dose\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-fi\"\u003e\n\u003cb class=\"pp-v2\"\u003e20 days (5,000iu) \/ 40 days (10,000iu)\u003c\/b\u003e\u003cspan\u003eOne vial lasts\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-fi\"\u003e\n\u003cb class=\"pp-v2\"\u003eIndependently HPLC tested\u003c\/b\u003e\u003cspan\u003eEvery batch\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec\" id=\"overview\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eOverview\u003c\/p\u003e\n\u003ch2\u003eIn plain English\u003c\/h2\u003e\n\u003cdiv class=\"pp-ov pp-prose\"\u003e\n\u003cp\u003eHCG is a hormone, not a peptide. It is best known from pregnancy testing, but in this context it is used because it acts on the same receptor as luteinising hormone — the signal that tells the testes to make testosterone.\u003c\/p\u003e\n\u003cp\u003eThe main use is alongside TRT: exogenous testosterone shuts down that signal, and HCG replaces it so the testes keep working. It is also used in fertility and post-cycle protocols.\u003c\/p\u003e\n\u003cul class=\"pp-tldr\"\u003e\n\u003cli\u003e\n\u003cb\u003eWhat it is\u003c\/b\u003e\u003cspan\u003eA glycoprotein hormone that mimics luteinising hormone\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eMainly used for\u003c\/b\u003e\u003cspan\u003eMaintaining testicular function and fertility on TRT\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eTypical protocol\u003c\/b\u003e\u003cspan\u003e250iu daily, reassessed with bloodwork every 8–12 weeks\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec pp-alt\" id=\"how\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cdiv class=\"pp-prose pp-wide\"\u003e\n\u003cp class=\"pp-kick\"\u003eHow it works\u003c\/p\u003e\n\u003ch2\u003eWhat it actually does\u003c\/h2\u003e\n\u003cp\u003eTestosterone production runs on a signal from the brain. When you take testosterone from outside, the brain sees enough and stops sending that signal — so the testes go quiet and shrink.\u003c\/p\u003e\n\u003cp\u003eHCG binds the same receptor as that signal. The testes carry on producing, and testicular volume and fertility are maintained.\u003c\/p\u003e\n\u003cp\u003eIt lasts far longer in the blood than the natural signal does, because of extra sugar chains and a longer tail on the molecule — which is why a small daily dose is enough.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdetails class=\"pp-ac pp-more\"\u003e\u003csummary\u003eThe science in detail\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\n\u003cp\u003eHCG is not a peptide in the sense that most of this catalogue is. It is a heterodimeric glycoprotein hormone, produced by the syncytiotrophoblast during pregnancy, and it belongs to the same structural family as luteinising hormone, follicle-stimulating hormone and thyroid-stimulating hormone. All four share a common alpha subunit; specificity resides entirely in the beta subunit, which associates non-covalently with the alpha chain to form the active hormone. Neither subunit is active alone.\u003c\/p\u003e\n\u003cp\u003eThe target is the luteinising hormone \/ choriogonadotropin receptor, a class A G-protein-coupled receptor expressed on Leydig cells in the testis and on theca and granulosa cells in the ovary. Receptor occupancy activates adenylate cyclase, raises cAMP and drives protein kinase A signalling, with steroidogenic acute regulatory protein mobilising cholesterol to the inner mitochondrial membrane as the rate-limiting step in steroid synthesis.\u003c\/p\u003e\n\u003cp\u003eHCG and LH act at the same receptor, which is why HCG functions experimentally as an LH surrogate. The pharmacologically significant difference is duration. The HCG beta subunit carries a C-terminal peptide extension bearing additional O-linked glycosylation, and this heavily sialylated tail markedly slows renal clearance. The result is a far longer circulating half-life than native LH, which is what makes the molecule useful as a sustained stimulus in gonadal research models.\u003c\/p\u003e\n\u003cp\u003eThe human literature is substantial and long-established. Matsumoto, Karpas and Bremner (Journal of Clinical Endocrinology \u0026amp; Metabolism, 1986) administered HCG chronically to normal men, suppressing FSH to undetectable levels, and demonstrated that FSH replacement was required to restore quantitatively normal sperm production — establishing the division of labour between the two gonadotropins. Coviello et al. (Journal of Clinical Endocrinology \u0026amp; Metabolism, 2005) reported that low-dose HCG maintained intratesticular testosterone in normal men with testosterone-induced gonadotropin suppression, a study frequently cited in subsequent work on gonadal axis suppression.\u003c\/p\u003e\n\u003cp\u003eBecause it is a glycoprotein rather than a synthetic peptide, batch characterisation and handling differ meaningfully from the rest of this catalogue.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/details\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eEvidence\u003c\/p\u003e\n\u003ch2\u003eWhat the research shows\u003c\/h2\u003e\n\u003cdiv class=\"pp-cards\"\u003e\n\u003cdiv class=\"pp-card\"\u003e\n\u003cspan class=\"pp-num\"\u003e01\u003c\/span\u003e\u003ch3\u003eActs on the same receptor as LH\u003c\/h3\u003e\n\u003cp\u003eIt substitutes for the brain's signal to the testes, which exogenous testosterone suppresses.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-card\"\u003e\n\u003cspan class=\"pp-num\"\u003e02\u003c\/span\u003e\u003ch3\u003eMuch longer-lasting than natural LH\u003c\/h3\u003e\n\u003cp\u003eStructural differences give it a far longer half-life, so low daily doses are effective.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-card\"\u003e\n\u003cspan class=\"pp-num\"\u003e03\u003c\/span\u003e\u003ch3\u003eLow doses maintain testicular testosterone\u003c\/h3\u003e\n\u003cp\u003eA published clinical study found intratesticular testosterone maintained at low HCG doses.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-card\"\u003e\n\u003cspan class=\"pp-num\"\u003e04\u003c\/span\u003e\u003ch3\u003eShares structure with LH, FSH and TSH\u003c\/h3\u003e\n\u003cp\u003eIt belongs to the same hormone family; only one half of the molecule gives it its specificity.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec pp-alt\" id=\"prep\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eMixing \u0026amp; dosage\u003c\/p\u003e\n\u003ch2\u003eHow to mix and dose it\u003c\/h2\u003e\n\u003cdiv class=\"pp-prose pp-wide\"\u003e\n\u003cp\u003eThese are the mixing and dosage instructions supplied by Purist Peptides and the manufacturer for this product.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eA 3ml vial of bacteriostatic water is included free with every peptide vial you order\u003c\/strong\u003e, so you have what you need to mix this on arrival.\u003c\/p\u003e\n\u003cdiv class=\"pp-vbox\"\u003e\n\u003ch3\u003eHCG 5,000iu\u003c\/h3\u003e\n\u003cp class=\"pp-sub\"\u003eStep 1 — mix your vial\u003c\/p\u003e\n\u003col class=\"pp-step\"\u003e\n\u003cli\u003eDraw up 1ml of bacteriostatic water into a syringe\u003c\/li\u003e\n\u003cli\u003eWipe the rubber top of your vial with an alcohol swab and let it dry\u003c\/li\u003e\n\u003cli\u003eInsert the needle then slowly and carefully push the water down the inside wall of the vial — do not inject water straight onto the peptide powder\u003c\/li\u003e\n\u003cli\u003eGently roll the vial between your palms until the powder dissolves completely\u003c\/li\u003e\n\u003cli\u003eDo not shake\u003c\/li\u003e\n\u003cli\u003eAllow to settle in the fridge for 5–10 minutes. The liquid should look clear\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"pp-sub\"\u003eStep 2 — draw \u0026amp; inject your dose\u003c\/p\u003e\n\u003cp\u003eUse a 1ml insulin syringe to draw and inject your dose. A 1ml syringe = 100 units.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWith 1ml of water added, each 0.1ml (10 units) you draw = 500iu of HCG.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"pp-dose\"\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eStage\u003c\/th\u003e\n\u003cth\u003eDose\u003c\/th\u003e\n\u003cth\u003eOn the syringe\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003eStandard\u003c\/td\u003e\n\u003ctd\u003e250iu daily\u003c\/td\u003e\n\u003ctd\u003e5 units\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003eVial duration at standard dose: 20 days\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhen to inject:\u003c\/strong\u003e Daily at a consistent time. Most commonly used alongside TRT to maintain testicular function.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCycle length:\u003c\/strong\u003e Ongoing as directed. Reassess with bloodwork every 8 to 12 weeks.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-vbox\"\u003e\n\u003ch3\u003eHCG 10,000iu\u003c\/h3\u003e\n\u003cp class=\"pp-sub\"\u003eStep 1 — mix your vial\u003c\/p\u003e\n\u003col class=\"pp-step\"\u003e\n\u003cli\u003eDraw up 2ml of bacteriostatic water into a syringe\u003c\/li\u003e\n\u003cli\u003eWipe the rubber top of your vial with an alcohol swab and let it dry\u003c\/li\u003e\n\u003cli\u003eInsert the needle then slowly and carefully push the water down the inside wall of the vial — do not inject water straight onto the peptide powder\u003c\/li\u003e\n\u003cli\u003eGently roll the vial between your palms until the powder dissolves completely\u003c\/li\u003e\n\u003cli\u003eDo not shake\u003c\/li\u003e\n\u003cli\u003eAllow to settle in the fridge for 5–10 minutes. The liquid should look clear\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"pp-sub\"\u003eStep 2 — draw \u0026amp; inject your dose\u003c\/p\u003e\n\u003cp\u003eUse a 1ml insulin syringe to draw and inject your dose. A 1ml syringe = 100 units.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWith 2ml of water added, each 0.1ml (10 units) you draw = 500iu of HCG.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"pp-dose\"\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eStage\u003c\/th\u003e\n\u003cth\u003eDose\u003c\/th\u003e\n\u003cth\u003eOn the syringe\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003eStandard\u003c\/td\u003e\n\u003ctd\u003e250iu daily\u003c\/td\u003e\n\u003ctd\u003e5 units\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003eVial duration at standard dose: 40 days\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhen to inject:\u003c\/strong\u003e Daily at a consistent time. Most commonly used alongside TRT to maintain testicular function.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCycle length:\u003c\/strong\u003e Ongoing as directed. Reassess with bloodwork every 8 to 12 weeks.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp class=\"pp-sub\"\u003eHow to inject\u003c\/p\u003e\n\u003col class=\"pp-step\"\u003e\n\u003cli\u003eWipe your injection site with an alcohol swab and let it dry\u003c\/li\u003e\n\u003cli\u003ePinch a small fold of skin on your abdomen\u003c\/li\u003e\n\u003cli\u003eInsert the needle at a 45-degree angle into the pinched skin\u003c\/li\u003e\n\u003cli\u003eSlowly push the plunger down until empty\u003c\/li\u003e\n\u003cli\u003ePull the needle out and apply gentle pressure with the swab\u003c\/li\u003e\n\u003cli\u003eDispose of the needle safely in a sharps container — never recap or reuse\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"pp-sub\"\u003eStorage\u003c\/p\u003e\n\u003cp\u003eKeep refrigerated at 2 to 6 degrees Celsius at all times after mixing. Do not freeze. Protect from light and label the vial with the date you reconstituted it. Discard any solution that is hazy, discoloured or contains particles.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor informational purposes only. This is not medical advice. Speak to a qualified healthcare professional before starting any compound.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cfigure class=\"pp-fig\"\u003e\u003cimg class=\"pp-img\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0984\/2422\/6090\/files\/purist-reconstitution-steps-v2.png?v=1786504935\" alt=\"Four-step peptide reconstitution guide: bring the vial to room temperature, add bacteriostatic water down the vial wall, roll gently without shaking, and store refrigerated at 2 to 6 degrees Celsius without freezing\" width=\"1400\" height=\"900\" loading=\"lazy\" decoding=\"async\"\u003e\u003c\/figure\u003e\n\u003cp style=\"margin-top:26px\"\u003e\u003ca class=\"pp-cta\" href=\"#specs\" onclick=\"window.scrollTo({top:0,behavior:'smooth'});return false;\"\u003eReady to order — back to the top\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec pp-alt\" id=\"faq\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eQuestions\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003cdiv class=\"pp-faq\"\u003e\n\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eWhy is HCG measured in international units rather than milligrams?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eBecause it is a glycoprotein whose activity depends on glycosylation as well as sequence, potency is defined against a biological reference standard rather than by mass. Two preparations of identical mass may differ in activity, so international units are the meaningful specification.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eHow does HCG differ from luteinising hormone?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eBoth act at the same receptor. The difference is duration: the HCG beta subunit carries a C-terminal peptide extension with additional sialylated O-linked glycans, which slows renal clearance substantially and gives a far longer circulating half-life than native LH.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eWhat has HCG been studied for in the research literature?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eGonadal steroidogenesis, intratesticular testosterone, and the respective roles of LH and FSH in spermatogenesis. Matsumoto et al. (JCEM, 1986) and Coviello et al. (JCEM, 2005) are two frequently cited examples. Purist supplies the compound for laboratory research only.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eWhy does it require different handling from the synthetic peptides?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eIt is a much larger molecule held together by a non-covalent association between two subunits. That association can be lost to shear or interfacial stress without any visible change in the solution, and activity is lost with it. Reconstituted stability windows are also shorter.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eHow is purity verified?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eEvery batch is assayed by independent HPLC at Bioindustrial Services in Boksburg. We do not rely on the manufacturer's own certificate alone. The assay report for the batch you receive is available on request, and our full testing protocol is set out at \u003ca href=\"\/pages\/quality-standards\"\u003eQuality Standards\u003c\/a\u003e.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eHow long does delivery take?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eOrders are dispatched from the Netherlands, with timelines varying by region and courier. Current dispatch and transit windows are set out at \u003ca href=\"\/pages\/delivery-process\"\u003eDelivery Process\u003c\/a\u003e.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eWhat is the returns policy?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eUnopened vials in original condition may be returned under the conditions set out at \u003ca href=\"\/pages\/return-refund-policy\"\u003eRefund Policy\u003c\/a\u003e.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-links\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eExplore\u003c\/p\u003e\n\u003cdiv class=\"pp-chips\"\u003e\n\u003ca class=\"pp-chip pp-chip-lead\" href=\"\/collections\/lean-muscle-growth-peptides\"\u003eAlso in Lean Muscle \u0026amp; Growth Hormone\u003c\/a\u003e\u003ca class=\"pp-chip\" href=\"\/products\/tesamorelin\"\u003eTesamorelin\u003c\/a\u003e\u003ca class=\"pp-chip\" href=\"\/products\/cjc-1295-w-dac\"\u003eCJC-1295 w DAC\u003c\/a\u003e\u003ca class=\"pp-chip pp-chip-alt\" href=\"\/pages\/hormone-optimisation-peptide-stack\"\u003eHormone Optimisation Peptide Stack\u003c\/a\u003e\u003ca class=\"pp-chip pp-chip-alt\" href=\"\/pages\/lean-growth-peptide-stack\"\u003eLean Growth Peptide Stack\u003c\/a\u003e\u003ca class=\"pp-chip pp-chip-alt\" href=\"\/pages\/gh-optimisation-peptide-stack\"\u003eGH Optimisation Peptide Stack\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003c\/div\u003e\n\u003cscript type=\"application\/ld+json\"\u003e{\"@context\":\"https:\/\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"Why is HCG measured in international units rather than milligrams?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Because it is a glycoprotein whose activity depends on glycosylation as well as sequence, potency is defined against a biological reference standard rather than by mass. Two preparations of identical mass may differ in activity, so international units are the meaningful specification.\"}},{\"@type\":\"Question\",\"name\":\"How does HCG differ from luteinising hormone?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Both act at the same receptor. The difference is duration: the HCG beta subunit carries a C-terminal peptide extension with additional sialylated O-linked glycans, which slows renal clearance substantially and gives a far longer circulating half-life than native LH.\"}},{\"@type\":\"Question\",\"name\":\"What has HCG been studied for in the research literature?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Gonadal steroidogenesis, intratesticular testosterone, and the respective roles of LH and FSH in spermatogenesis. Matsumoto et al. (JCEM, 1986) and Coviello et al. (JCEM, 2005) are two frequently cited examples. Purist supplies the compound for laboratory research only.\"}},{\"@type\":\"Question\",\"name\":\"Why does it require different handling from the synthetic peptides?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"It is a much larger molecule held together by a non-covalent association between two subunits. That association can be lost to shear or interfacial stress without any visible change in the solution, and activity is lost with it. Reconstituted stability windows are also shorter.\"}},{\"@type\":\"Question\",\"name\":\"How is purity verified?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Every batch is assayed by independent HPLC at Bioindustrial Services in Boksburg. We do not rely on the manufacturer's own certificate alone. The assay report for the batch you receive is available on request, and our full testing protocol is set out at https:\/\/puristpeptides.nl\/pages\/quality-standards.\"}},{\"@type\":\"Question\",\"name\":\"How long does delivery take?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Orders are dispatched from the Netherlands, with timelines varying by region and courier. Current dispatch and transit windows are set out at https:\/\/puristpeptides.nl\/pages\/delivery-process.\"}},{\"@type\":\"Question\",\"name\":\"What is the returns policy?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Unopened vials in original condition may be returned under the conditions set out at https:\/\/puristpeptides.nl\/pages\/return-refund-policy.\"}}]}\u003c\/script\u003e","brand":"Purist Peptides","offers":[{"title":"Default Title","offer_id":51362501787871,"sku":"PP-HCG-01","price":59.95,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/8787\/3759\/files\/purist-peptides-hcg-5000iu-gonadotropin-hormone-research-peptide-vial.jpg?v=1789020693","url":"https:\/\/puristpeptides.nl\/products\/hcg","provider":"Purist Peptides NL","version":"1.0","type":"link"}