{"product_id":"selank","title":"Selank","description":"\u003cstyle\u003e.pp-pdp{--nv:#0d2233;--tl:#3a9ab5;--ink:#1f2937;--mut:#5b6b7a;--ln:#e3e8ee;--sf:#f5f8fa;--gr:#1E9E5A;font-family:Montserrat,-apple-system,sans-serif;color:var(--ink);line-height:1.6;margin:34px 0 0;width:100%;max-width:100%;overflow-x:hidden;background:#fff;text-align:left}.pp-pdp *{box-sizing:border-box}.pp-pdp h2,.pp-pdp h3{color:var(--nv);font-weight:800;line-height:1.15;margin:0 0 14px}.pp-pdp p{color:var(--ink);margin:0 0 14px}.pp-pdp p:last-child{margin-bottom:0}.pp-pdp a{color:#0d6c8a}.pp-pdp .pp-in{max-width:1180px;margin:0 auto;padding:0 24px}.pp-pdp .pp-kick{color:var(--tl);font-size:12px;letter-spacing:2.16px;text-transform:uppercase;font-weight:600;margin:0 0 12px}.pp-pdp .pp-sec{padding:56px 0}.pp-pdp .pp-alt{background:var(--sf)}.pp-pdp .pp-sec h2{font-size:30px}.pp-pdp .pp-prose p{font-size:15.5px;color:var(--mut)}.pp-pdp .pp-prose p strong{color:var(--nv)}.pp-pdp .pp-wide{max-width:900px}.pp-pdp 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18px}.pp-pdp .pp-facts .pp-in{grid-template-columns:repeat(2,1fr);gap:18px}.pp-pdp .pp-fi{border-left:0;text-align:left;padding:0}.pp-pdp .pp-fi .pp-v1{font-size:22px}.pp-pdp .pp-cards{grid-template-columns:1fr} } @media(max-width:520px){.pp-pdp .pp-facts .pp-in{grid-template-columns:1fr}}.pp-pdp .pp-ov{border-left:4px solid var(--tl);background:var(--sf);border-radius:0 12px 12px 0;padding:26px 28px;max-width:900px}.pp-pdp .pp-ov p{font-size:16px;color:var(--ink)}.pp-pdp .pp-tldr{list-style:none;margin:18px 0 0;padding:16px 0 0;border-top:1px solid var(--ln)}.pp-pdp .pp-tldr li{display:flex;gap:14px;padding:6px 0;font-size:14.5px;color:var(--mut)}.pp-pdp .pp-tldr b{color:var(--nv);flex:0 0 148px}.pp-pdp .pp-card h3{font-size:15.5px;margin:0 0 8px;color:var(--nv);line-height:1.3}.pp-pdp .pp-more{margin-top:24px;max-width:900px}.pp-pdp .pp-more .pp-ab p{margin-bottom:12px}.pp-pdp .pp-dose{width:100%;border-collapse:collapse;margin:0 0 16px}.pp-pdp .pp-dose th,.pp-pdp .pp-dose td{text-align:left;padding:11px 14px;border-bottom:1px solid var(--ln);font-size:14.5px;color:var(--mut)}.pp-pdp .pp-dose th{background:var(--nv);color:#fff;font-size:11.5px;letter-spacing:1.2px;text-transform:uppercase;font-weight:700}.pp-pdp .pp-dose td:first-child{font-weight:700;color:var(--nv);white-space:nowrap}.pp-pdp .pp-step{counter-reset:s;list-style:none;padding:0;margin:0 0 18px}.pp-pdp .pp-step li{position:relative;padding:0 0 11px 34px;font-size:15px;color:var(--mut)}.pp-pdp .pp-step li:before{counter-increment:s;content:counter(s);position:absolute;left:0;top:1px;width:22px;height:22px;border-radius:50%;background:var(--tl);color:#fff;font-size:12px;font-weight:800;display:flex;align-items:center;justify-content:center}.pp-pdp .pp-warn{background:#fff6e5;border-left:4px solid #e0a33a;padding:13px 18px;border-radius:0 8px 8px 0;font-size:14.5px;color:var(--ink);margin:0 0 16px}.pp-pdp .pp-warn p{margin:0 0 6px;font-size:14.5px}.pp-pdp .pp-warn p:last-child{margin:0}.pp-pdp .pp-vbox{border:1px solid var(--ln);border-radius:12px;padding:26px;margin:0 0 22px;background:#fff;box-shadow:0 2px 10px rgba(13,34,51,.05)}.pp-pdp .pp-vbox h3{font-size:18px;margin:0 0 18px;padding-bottom:12px;border-bottom:2px solid var(--tl)}.pp-pdp .pp-vbox p{font-size:15px}.pp-pdp .pp-sub{font-size:12px;letter-spacing:1.5px;text-transform:uppercase;font-weight:800;color:var(--tl);margin:0 0 10px}.pp-pdp .pp-cta{display:inline-block;background:var(--gr);color:#fff!important;font-weight:800;font-size:15px;padding:15px 32px;border-radius:6px;text-decoration:none;margin-top:8px}.pp-pdp .pp-cta:hover{filter:brightness(1.08)}@media(max-width:900px){.pp-pdp .pp-tldr li{display:block}.pp-pdp .pp-tldr b{display:block;margin-bottom:2px}.pp-pdp .pp-vbox{padding:20px}.pp-pdp .pp-ov{padding:22px}}\u003c\/style\u003e\n\u003cdiv class=\"pp-pdp\"\u003e\n\u003csection class=\"pp-facts\" id=\"specs\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cdiv class=\"pp-fi\"\u003e\n\u003cb class=\"pp-v3\"\u003eGABAergic signalling research\u003c\/b\u003e\u003cspan\u003eResearch area\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-fi\"\u003e\n\u003cb class=\"pp-v2\"\u003e10mg\u003c\/b\u003e\u003cspan\u003ePer vial\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-fi\"\u003e\n\u003cb class=\"pp-v2\"\u003eTuftsin analogue\u003c\/b\u003e\u003cspan\u003eStructure\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-fi\"\u003e\n\u003cb class=\"pp-v2\"\u003eIndependently HPLC tested\u003c\/b\u003e\u003cspan\u003eEvery batch\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec\" id=\"overview\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eOverview\u003c\/p\u003e\n\u003ch2\u003eIn plain English\u003c\/h2\u003e\n\u003cdiv class=\"pp-ov pp-prose\"\u003e\n\u003cp\u003eSelank is a synthetic seven-amino-acid peptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) developed in Russia. It is an analogue of tuftsin, a naturally occurring immunomodulatory peptide.\u003c\/p\u003e\n\u003cp\u003eIt is studied in preclinical and clinical research for modulation of GABAergic signalling, for anxiolytic-like effects in preclinical models, and for effects on enkephalin-degrading enzymes. Strictly for laboratory research use. Not for human or veterinary consumption.\u003c\/p\u003e\n\u003cul class=\"pp-tldr\"\u003e\n\u003cli\u003e\n\u003cb\u003eWhat it is\u003c\/b\u003e\u003cspan\u003eA synthetic heptapeptide analogue of the peptide tuftsin\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eMainly studied for\u003c\/b\u003e\u003cspan\u003eGABAergic signalling, enkephalin-degrading enzymes\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eResearch protocol\u003c\/b\u003e\u003cspan\u003eTo be published shortly. Contact us for details\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec pp-alt\" id=\"how\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cdiv class=\"pp-prose pp-wide\"\u003e\n\u003cp class=\"pp-kick\"\u003eHow it works\u003c\/p\u003e\n\u003ch2\u003eWhat it actually does\u003c\/h2\u003e\n\u003cp\u003eSelank begins with the four residues of tuftsin (Thr-Lys-Pro-Arg) and ends in a Pro-Gly-Pro extension at the C-terminus, the same stabilising motif used in Semax.\u003c\/p\u003e\n\u003cp\u003eResearch interest centres on GABAergic signalling, the brain’s main inhibitory neurotransmitter system, and on anxiolytic-like effects observed in preclinical models.\u003c\/p\u003e\n\u003cp\u003eSelank has also been studied for its effects on enzymes that break down enkephalins, the body’s own opioid peptides.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdetails class=\"pp-ac pp-more\"\u003e\u003csummary\u003eThe science in detail\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\n\u003cp\u003eTuftsin is a naturally occurring tetrapeptide (Thr-Lys-Pro-Arg) released from the heavy chain of immunoglobulin G, and is known for immunomodulatory activity. Selank was developed in Russia by extending this sequence with a C-terminal Pro-Gly-Pro motif, giving the heptapeptide Thr-Lys-Pro-Arg-Pro-Gly-Pro.\u003c\/p\u003e\n\u003cp\u003eThe Pro-Gly-Pro extension is intended to improve stability: short peptides such as tuftsin are rapidly degraded by peptidases, and the added tail slows that breakdown in experimental systems.\u003c\/p\u003e\n\u003cp\u003eMechanistic studies have focused on GABAergic signalling. Work in rodents has reported changes in the expression of genes involved in GABAergic neurotransmission, and Selank has been examined for anxiolytic-like effects in preclinical behavioural models.\u003c\/p\u003e\n\u003cp\u003eA separate line of research concerns enkephalin-degrading enzymes. Selank has been reported to inhibit enzymes that break down enkephalins, which would be expected to prolong the activity of these endogenous opioid peptides. As with Semax, much of the literature comes from Russian research groups.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/details\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eEvidence\u003c\/p\u003e\n\u003ch2\u003eWhat the research shows\u003c\/h2\u003e\n\u003cdiv class=\"pp-cards\"\u003e\n\u003cdiv class=\"pp-card\"\u003e\n\u003cspan class=\"pp-num\"\u003e01\u003c\/span\u003e\u003ch3\u003eBuilt on tuftsin\u003c\/h3\u003e\n\u003cp\u003eSelank extends tuftsin, a four-residue immunomodulatory peptide, into a heptapeptide.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-card\"\u003e\n\u003cspan class=\"pp-num\"\u003e02\u003c\/span\u003e\u003ch3\u003eStabilised by Pro-Gly-Pro\u003c\/h3\u003e\n\u003cp\u003eThe same C-terminal extension used in Semax was added to slow enzymatic breakdown.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-card\"\u003e\n\u003cspan class=\"pp-num\"\u003e03\u003c\/span\u003e\u003ch3\u003eGABAergic signalling\u003c\/h3\u003e\n\u003cp\u003eRodent studies report changes in GABA-related gene expression and anxiolytic-like effects.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-card\"\u003e\n\u003cspan class=\"pp-num\"\u003e04\u003c\/span\u003e\u003ch3\u003eEnkephalin-degrading enzymes\u003c\/h3\u003e\n\u003cp\u003eSelank has been reported to inhibit enzymes that break down enkephalins.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec pp-alt\" id=\"prep\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eMixing \u0026amp; dosage\u003c\/p\u003e\n\u003ch2\u003eHow to mix and dose it\u003c\/h2\u003e\n\u003cdiv class=\"pp-prose pp-wide\"\u003e\n\u003cp\u003eReconstitution and research protocol for this compound will be published here shortly. Contact us for details.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eStrictly for laboratory research use. Not for human or veterinary consumption.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp style=\"margin-top:26px\"\u003e\u003ca class=\"pp-cta\" href=\"#specs\" onclick=\"window.scrollTo({top:0,behavior:'smooth'});return false;\"\u003eReady to order — back to the top\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-sec pp-alt\" id=\"faq\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eQuestions\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003cdiv class=\"pp-faq\"\u003e\n\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eWhat is Selank studied for?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003ePublished work covers modulation of GABAergic signalling, anxiolytic-like effects in preclinical behavioural models, and inhibition of enkephalin-degrading enzymes. Much of the literature originates from Russian research groups. Purist supplies the compound for laboratory research only.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eHow does Selank relate to tuftsin?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eTuftsin is a naturally occurring immunomodulatory tetrapeptide, Thr-Lys-Pro-Arg. Selank keeps that sequence and adds a Pro-Gly-Pro extension, giving the heptapeptide Thr-Lys-Pro-Arg-Pro-Gly-Pro.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eWhy does Selank carry a Pro-Gly-Pro extension?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eShort peptides are rapidly degraded by peptidases. The Pro-Gly-Pro C-terminal extension was added to improve stability against that breakdown in experimental systems. Semax carries the same extension.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eHow does Selank differ from Semax?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eBoth are synthetic heptapeptides developed in Russia that end in Pro-Gly-Pro. Selank is derived from tuftsin and is researched mainly for GABAergic signalling; Semax is derived from the ACTH(4–10) fragment and is researched mainly for neurotrophic signalling.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eHow is purity verified?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eEvery batch is assayed by independent HPLC at Bioindustrial Services. We do not rely on the manufacturer's own certificate alone. The assay report for the batch you receive is available on request, and our full testing protocol is set out at \u003ca href=\"\/pages\/quality-standards\"\u003eQuality Standards\u003c\/a\u003e.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eHow long does delivery take?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eOrders are dispatched from the Netherlands with tracked courier delivery — 1–3 business days within the Netherlands, 2–5 business days to the rest of the EU. Current dispatch and transit windows are set out at \u003ca href=\"\/pages\/delivery-process\"\u003eDelivery Process\u003c\/a\u003e.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"pp-ac\"\u003e\u003csummary\u003eWhat is the returns policy?\u003c\/summary\u003e\u003cdiv class=\"pp-ab\"\u003e\u003cp\u003eUnopened vials in original condition may be returned under the conditions set out at \u003ca href=\"\/pages\/return-refund-policy\"\u003eRefund Policy\u003c\/a\u003e.\u003c\/p\u003e\u003c\/div\u003e\u003c\/details\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"pp-links\"\u003e\u003cdiv class=\"pp-in\"\u003e\n\u003cp class=\"pp-kick\"\u003eExplore\u003c\/p\u003e\n\u003cdiv class=\"pp-chips\"\u003e\n\u003ca class=\"pp-chip pp-chip-lead\" href=\"\/collections\/sleep-mood-peptides\"\u003eAlso in Sleep, Stress \u0026amp; Circadian\u003c\/a\u003e\u003ca class=\"pp-chip\" href=\"\/products\/semax\"\u003eSemax\u003c\/a\u003e\u003ca class=\"pp-chip\" href=\"\/products\/dsip\"\u003eDSIP\u003c\/a\u003e\u003ca class=\"pp-chip pp-chip-alt\" href=\"\/collections\/all-peptides\"\u003eThe Full Purist Range\u003c\/a\u003e\u003ca class=\"pp-chip pp-chip-alt\" href=\"\/pages\/quality-standards\"\u003eQuality Standards\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003c\/div\u003e\n\u003cscript type=\"application\/ld+json\"\u003e{\"@context\": \"https:\/\/schema.org\", \"@type\": \"FAQPage\", \"mainEntity\": [{\"@type\": \"Question\", \"name\": \"What is Selank studied for?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Published work covers modulation of GABAergic signalling, anxiolytic-like effects in preclinical behavioural models, and inhibition of enkephalin-degrading enzymes. Much of the literature originates from Russian research groups. Purist supplies the compound for laboratory research only.\"}}, {\"@type\": \"Question\", \"name\": \"How does Selank relate to tuftsin?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Tuftsin is a naturally occurring immunomodulatory tetrapeptide, Thr-Lys-Pro-Arg. Selank keeps that sequence and adds a Pro-Gly-Pro extension, giving the heptapeptide Thr-Lys-Pro-Arg-Pro-Gly-Pro.\"}}, {\"@type\": \"Question\", \"name\": \"Why does Selank carry a Pro-Gly-Pro extension?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Short peptides are rapidly degraded by peptidases. The Pro-Gly-Pro C-terminal extension was added to improve stability against that breakdown in experimental systems. Semax carries the same extension.\"}}, {\"@type\": \"Question\", \"name\": \"How does Selank differ from Semax?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Both are synthetic heptapeptides developed in Russia that end in Pro-Gly-Pro. Selank is derived from tuftsin and is researched mainly for GABAergic signalling; Semax is derived from the ACTH(4–10) fragment and is researched mainly for neurotrophic signalling.\"}}, {\"@type\": \"Question\", \"name\": \"How is purity verified?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Every batch is assayed by independent HPLC at Bioindustrial Services. We do not rely on the manufacturer's own certificate alone. The assay report for the batch you receive is available on request, and our full testing protocol is set out at \/pages\/quality-standards.\"}}, {\"@type\": \"Question\", \"name\": \"How long does delivery take?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Orders are dispatched from the Netherlands with tracked courier delivery — 1–3 business days within the Netherlands, 2–5 business days to the rest of the EU. Current dispatch and transit windows are set out at \/pages\/delivery-process.\"}}, {\"@type\": \"Question\", \"name\": \"What is the returns policy?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Unopened vials in original condition may be returned under the conditions set out at \/pages\/return-refund-policy.\"}}]}\u003c\/script\u003e","brand":"Purist Peptides","offers":[{"title":"10mg","offer_id":51435020550367,"sku":"PP-SELANK-10","price":49.95,"currency_code":"EUR","in_stock":false}],"url":"https:\/\/puristpeptides.nl\/products\/selank","provider":"Purist Peptides NL","version":"1.0","type":"link"}